β-Elemonic Acid

β-Elemonic Acid 구조식 이미지
카스 번호:
28282-25-9
상품명:
β-Elemonic Acid
동의어(영문):
β-Elemonic;Beta-EleMonic;elemonic acid;β-deMonic acid;β-demonic-acid;B-ELEMONIC ACID;β-Elemonic acid;β-Elemonic acid;Elemadienonic acid;BETA-ELEMONIC ACID
CBNumber:
CB6737997
분자식:
C30H46O3
포뮬러 무게:
454.68
MOL 파일:
28282-25-9.mol
MSDS 파일:
SDS

β-Elemonic Acid 속성

녹는점
224-225°C
끓는 점
565.2±50.0 °C(Predicted)
밀도
1.07
저장 조건
2-8°C
용해도
DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
4.65±0.10(Predicted)
색상
White to off-white

안전

β-Elemonic Acid C화학적 특성, 용도, 생산

개요

β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro.

용도

β-Elemonic Acid inhibits cell proliferation of human lung adenocarcinoma A549 cells and role of MAPK, ROS activation and glutathione depletion. Elemonic acid is also a Pin1 inhibitors.

β-Elemonic Acid 준비 용품 및 원자재

원자재

준비 용품


β-Elemonic Acid 공급 업체

글로벌( 143)공급 업체
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Shanghai Zheyan Biotech Co., Ltd.
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Chengdu Greenpure Biopharma CO.,Ltd
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Chengdu GLP biotechnology Co Ltd
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Chengdu Biopurify Phytochemicals Ltd.
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Xi'an Kono chem co., Ltd.,
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career henan chemical co
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marketing1@neostarunited.com China 12126 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58

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