G-STROPHANTHIN
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G-STROPHANTHIN 속성
- 녹는점
- 200°C
- 끓는 점
- 561.69°C (rough estimate)
- 밀도
- 1.1941 (rough estimate)
- 굴절률
- -32 ° (C=1, H2O)
- 저장 조건
- Desiccate at -20°C
- 용해도
- H2O: 차가운 10 mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 13.04±0.70(Predicted)
- 색상
- 하얀색
- 수용성
- 13g/L(25℃)
- Merck
- 6901
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T | ||
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위험 카페고리 넘버 | 23/25-33 | ||
안전지침서 | 45 | ||
유엔번호(UN No.) | UN 1544 6.1/PG 1 | ||
WGK 독일 | 3 | ||
RTECS 번호 | RN3850000 | ||
F 고인화성물질 | 8 | ||
유해 물질 데이터 | 630-60-4(Hazardous Substances Data) | ||
독성 | LD50 oral in guinea pig: 8280ug/kg |
그림문자(GHS): |
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신호 어: | Danger | ||||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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G-STROPHANTHIN C화학적 특성, 용도, 생산
개요
One of several cardiac glycosides that have been used clinically as cardiotonic agents and diuretics. Ouabain is obtained from the seeds of Strophanthus gratus, Acokanthera ouabaio, and related species. It was formerly prescribed under the name strophanthuis as the purified seed extract.화학적 성질
Ouabain is a white crystalline solid.일반 설명
Odorless, white crystals or crystalline powder as an octahydrate. Used to produce rapid digitalization in acute congestive heart failure. Also recommended in treatment of atrial or nodal paroxysmal tachycardia and atrial flutter.반응 프로필
When heated to decomposition, G-STROPHANTHIN emits acrid smoke and fumes. Hydrolysis yields one mole ouabagenin and one mole rhamnose. Stable in air, but affected by light (G-STROPHANTHIN octahydrate) [EPA, 1998].건강위험
G-STROPHANTHIN is classified as extremely toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste (less than 7 drops) for 70 kg (150-lb.) person. Exposure may result in respiratory and cardiac failure, and/or hyperalkemia. Patients with frequent premature ventricular heart beats or who have received any preparation of digitalis during preceding three weeks are prone to toxicity.화재위험
When heated to decomposition, G-STROPHANTHIN emits acrid smoke and fumes. Hydrolysis yields one mole ouabagenin and one mole rhamnose. Stable in air, but affected by light (G-STROPHANTHIN octahydrate)생물학적 활성
Selective Na + , K + -ATPase inhibitor.Safety Profile
Poison by ingestion, intramuscular, intraperitoneal, intravenous, subcutaneous, and parented routes. Moderately toxic by intraduodenal route. A cardac stimulant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes잠재적 노출
Ouabain, similar to digitoxin, is used to produce rapid digitalization in acute congestive heart failure. Also recommended in treatment of atrial or nodal paroxysmal tachycardia and atrial flutter; enzyme inhibitor.운송 방법
UN1544 Alkaloids, solid, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.Purification Methods
It crystallises from water as the octahydrate. Dry it at 130o. It decomposes at 190o when dry. Store it in the dark as it is light sensitive, but it is stable in air. Its solubility (g/100mL) in H2O is 1.3 (~25o), 20 (~100o), and in EtOH it is 1.0 (~25o) and 12.5 (~78o). It is highly TOXIC as it is an inhibitor of cation transport and of Na+ and K+ ATPase. [Beilstein 18/5 V 625.]비 호환성
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.).G-STROPHANTHIN 준비 용품 및 원자재
원자재
준비 용품
G-STROPHANTHIN 공급 업체
글로벌( 66)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
TopScience Biochemical | 00852-68527855 |
info@itopbiochem.com | China Hong Kong | 902 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 8853 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15395 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
LGM Pharma | 1-(800)-881-8210 |
inquiries@lgmpharma.com | United States | 2127 | 70 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 |
waley188@sohu.com | China | 12338 | 58 |
G-STROPHANTHIN 관련 검색:
STROPHANTHIN 3ALPHA-1-RHAMNOSIDE
OUABAGENIN
DIHYDRO-G-STROPHANTHIN
K-strophanthin variable mixture
K-STROPHANTHIN,STROPHANTHIN K,kombe-strophanthi
STROPHANTHIDIN
K-STROPHANTHIN-A,STROPHANTHIN K,K STROPHANTHIN,K-STROPHANTHIN-ALPHA
G-STROPHANTHIN
OUABAIN OCTAHYDRATE
OUABAIN [3H(G)]
STROPHANTHIN, g-(RG)
D-Strophanthin
technetium Tc 99m K-strophanthin-beta
K-STROPHANTHIN STANDARDIZED MIXTURE
STROPHANTHIN,K-strophanthin-beta
9-ANTHROYL OUABAIN
BODIPY(R) FL OUABAIN