Senaparib

Senaparib 구조식 이미지
카스 번호:
1401682-78-7
상품명:
Senaparib
동의어(영문):
IMP4297;IMP 4297;IMP-4297;Senaparib;Senaparib (IMP-4297);Rotundine Impurity 13;Senaparib(IMP4297,JS109);5-Fluoro-1-(4-fluoro-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)quinazoline-2,4(1H,3H)-dione;inhibit,poly ADP ribose polymerase,IMP 4297,Inhibitor,breast,pancreatic,IMP-4297,Senaparib,PARP,cancer,PCa;2,4(1H,3H)-Quinazolinedione, 5-fluoro-1-[[4-fluoro-3-[[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl]phenyl]methyl]-
CBNumber:
CB68080026
분자식:
C24H20F2N6O3
포뮬러 무게:
478.45
MOL 파일:
1401682-78-7.mol

Senaparib 속성

저장 조건
Store at -20°C
용해도
DMSO : 83.33 mg/mL (174.17 mM; Need ultrasonic)
물리적 상태
Solid
색상
White to off-white

안전

Senaparib C화학적 특성, 용도, 생산

개요

Senaparib is a novel and potent PARP1 inhibitor with a unique chemical structure and high inhibitory activity. Research has found that Senaparib not only effectively inhibits the enzymatic activity of PARP1 and PARP2 but also induces the "trapping" of PARP1 on DNA, leading to the stalling of DNA replication forks and double-strand DNA breaks, ultimately causing cell death. This "trapping" effect is considered a key factor in the therapeutic efficacy of PARP1 inhibitors.

Senaparib 준비 용품 및 원자재

원자재

준비 용품


Senaparib 공급 업체

글로벌( 23)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238
sales@sun-shinechem.com China 985 64
Shanghai Biolang biotechnology Co.,Ltd 17764003753
2326587775@qq.com China 188 55
Shanghai Biolang biotechnology Co.,Ltd 17764003753
2326587775@qq.com China 188 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994
2853530910@QQ.com China 8012 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
sales@rechemscience.com China 2991 58
Wuhan Sun-shine Bio-technology Corporation Limited +86-027-6552-2453
sales@sun-shinechem.com China 727 58

Copyright 2019 © ChemicalBook. All rights reserved