2-hydroxypentanedioic acid
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2-hydroxypentanedioic acid 속성
- 녹는점
- >290?C (dec.)
- 저장 조건
- 2-8°C 2-8°C
- 용해도
- 메탄올(약간 용해됨), 물(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- 수용성
- 물에 100mM까지 용해됨
안전
| WGK 독일 | 3 |
|---|
2-hydroxypentanedioic acid C화학적 특성, 용도, 생산
개요
α-Hydroxyglutaric acid (2-HG) is an α-hydroxy acid. It is metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased levels of L-2-hydroxyglutaric acid . 2-HG can also be metabolized from isocitrate by mutated forms of isocitrate dehydrogenase 1 (IDH1) and IDH2. 2-HG is structurally similar to α-ketoglutarate, the product of wild-type isocitrate dehydrogenases, and competitively inhibits α-ketoglutarate-dependent dioxygenases, including histone lysine demethylases and DNA hydroxylases.화학적 성질
White to Off-White Solid용도
2-Hydroxyglutaric acid is a potential inhibitor of glutamate carboxypeptidase.2-hydroxypentanedioic acid 준비 용품 및 원자재
원자재
준비 용품
2-hydroxypentanedioic acid 공급 업체
글로벌( 43)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 |
info@sagechem.com | China | 10269 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 |
rs@raise-chem.com | China | 3374 | 55 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 |
info@adooq.com | United States | 2784 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Chengdu Chuangkecheng Biological Technology Co., Ltd. | 028-028-0000000 13008177686 |
sales@ckcbiotech.com | China | 738 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
| Beyond Pharmaceutical Co., Ltd | +86-0571-81953185; 15381198709 15381198709 |
jasonyao@beyond-pharma.com | China | 837 | 60 |