티로트리신

티로트리신
티로트리신 구조식 이미지
카스 번호:
1404-88-2
한글명:
티로트리신
동의어(한글):
티로트리신
상품명:
TYROTHRICIN
동의어(영문):
dermotricine;tyri10;coltirot;tyroderm;martricin;solutricine;soluthricin;bactratycin;TYROTHRICIN;hydrotricine
CBNumber:
CB7196704
분자식:
C6H13NO5
포뮬러 무게:
179.17112
MOL 파일:
1404-88-2.mol

티로트리신 속성

저장 조건
Store at -20°C
용해도
물에는 거의 녹지 않으며, 에탄올(96%)과 메탄올에는 녹습니다.
물리적 상태
Solid
색상
White to off-white
EPA
Tyrothricin (1404-88-2)

안전

안전지침서 22-24/25
WGK 독일 2
RTECS 번호 YP2975000
독성 LD50 in mice (mg/kg): >1500 s.c.; 100 i.p.; >3000 orally (Sous)

티로트리신 C화학적 특성, 용도, 생산

화학적 성질

White or almost white powder.

용도

Tyrothricin is a complex of two unrelated peptide families, gramicidin complex and tyrocidines complex, produced by Bacillus brevis and discovered by Dubos in 1939. Typically, tyrothricin is composed of 20% of the linear pentadecylpeptide gramicidins and 80% of cyclic decapeptide tyrocidines. Both the gramicidins and tyrocidines act by disrupting bacterial cell wall integrity, but by differing mechanisms. Tyrothricin is used clinically for bacterial skin infections in some countries.

정의

An antibiotic produced by growth of Bacillus brevis. It consists of a mixture of antibiotics, principally gramicidin and tyrocidine. Gramicidin is the more active component. Use is generally limited to local external applications. It is active against some Gram-positive bacteria, including species of pneumococci, streptococci, and staphylococci.

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