탁799

탁799
탁799 구조식 이미지
카스 번호:
229005-80-5
한글명:
탁799
동의어(한글):
탁799
상품명:
Tak 799
동의어(영문):
CS-2889;Tak 799;Takeda 779;TAK-779(Cl);TAK 799 ;TAK 779;TAK-779 >=98% (HPLC);TAK-779;TAK 779;TAK779;TAK779;TAK 799;TAKEDA 779;TAK-779 Chemical Structure;N,N-Dimethyl-N-(4-(2-(p-tolyl)-6,7-dihydro-5H-benzo[7]annulene-8-carboxamido)benzyl)tetrahydro-2H-pyran-4-aminium chloride
CBNumber:
CB72497117
분자식:
C33H39N2O2.Cl
포뮬러 무게:
531.136
MOL 파일:
229005-80-5.mol
MSDS 파일:
SDS

탁799 속성

저장 조건
2-8°C
용해도
H2O: 가용성3mg/mL, 투명(따뜻한)
물리적 상태
가루
색상
흰색에서 베이지색

안전

WGK 독일 3

탁799 C화학적 특성, 용도, 생산

용도

TAK-779 has been used to inhibit CC chemokine ligand 5 (CCL5)– C-C chemokine receptor type 5 (CCR5) interaction in vitro in natural killer (NK) cytotoxicity assay. It has also been used as a blocker of CCR5 to study its effects and to evaluate the opening of the Panx-1 channels on peripheral blood mononuclear cells (PBMCs) isolated from human immunodeficiency virus (HIV)-infected individuals.

Biochem/physiol Actions

TAK-779 is a potent, dual antagonist at chemokine receptors C-C chemokine receptor type 2 (CCR2) and C-C chemokine receptor type 5 (CCR5) with IC50 = 1.4 nM at CCR5 and 2.3 nM at CCR2. Antagonists of both CCR2 and CCR5 such as TAK-779 have been investigated for treatment of viruses, rheumatoid arthritis, multiple sclerosis, and cancer. CCR5 is particularly targeted for anti-HIV therapy, since HIV entry into cells requires chemokine coreceptors CCR5 and C-X-C motif chemokine receptor 4 (CXCR4).

탁799 준비 용품 및 원자재

원자재

준비 용품


탁799 공급 업체

글로벌( 63)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ATK CHEMICAL COMPANY LIMITED
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ivan@atkchemical.com China 32951 60
TargetMol Chemicals Inc.
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marketing@targetmol.com United States 32072 58
Career Henan Chemica Co
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laboratory@coreychem.com China 30241 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
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sales@molcore.com China 49734 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38465 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52925 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58

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