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STK393606

STK393606 구조식 이미지

카스 번호:: 355827-05-3

상품명:: STK393606

동의어(영문):: STK393606;2-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-ylsulfanylmethyl)-benzonitrile;2-[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)sulfanylmethyl]benzonitrile;Benzonitrile, 2-[[(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]-

CBNumber:: CB73152749

분자식:: C14H9BrN4S

포뮬러 무게:: 345.22

MOL 파일:: 355827-05-3.mol

속성

안전

용도

공급 업체 21

STK393606 속성

끓는 점: 548.0±60.0 °C(Predicted)

밀도: 1.70±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: ≤12mg/ml in DMSO;14mg/ml in dimethyl formamide

물리적 상태: 결정질 고체

산도 계수 (pKa): 7.45±0.40(Predicted)

안전

STK393606 C화학적 특성, 용도, 생산

개요

15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH) is a key enzyme involved in the inactivation of PGs and related eiscosanoids. It functions by catalyzing the oxidation of primary PGs to their 15-keto metabolites. Two types of 15-hydroxy PGDH have been identified: type-I is NAD⁺-dependent primarily using eicosanoids as substrates, while type-II uses either NAD⁺ or NADP⁺ as cofactors and bears broader substrate specificity. STK393606 is a competitive inhibitor of NAD⁺-dependent type-I 15-hydroxy PGDH with an IC₅₀ value of 26.4 nM and a K_i value of 5 nM. It demonstrates selectivity for 15-hydroxy PGDH when profiled across a panel of related dehydrogenase or reductase enzymes.

STK393606 준비 용품 및 원자재

원자재

준비 용품

STK393606 공급 업체

글로벌( 21)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8736	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58