히스톤유형VIII-S

히스톤유형VIII-S
히스톤유형VIII-S 구조식 이미지
카스 번호:
9064-47-5
한글명:
히스톤유형VIII-S
동의어(한글):
히스톤유형VIII-S
상품명:
HISTONE TYPE VIII-S
동의어(영문):
Histone,Nucleo;f3histonefraction;HISTONE TYPE III-S;HISTONE TYPE III-SS;HISTONE TYPE VIII-S;histoneiii(calfthymus);Histones,dried(Calf thyMus);Histone III (calfthyMus) (9CI);Histones nucleo froM calf thyMus;histone type iii-S from calf thymus
CBNumber:
CB7333970
분자식:
NULL
포뮬러 무게:
0
MOL 파일:
Mol file

히스톤유형VIII-S 속성

저장 조건
2-8°C
용해도
H2O: 가용성 10mg/mL, 투명~흐릿함, 무색~연황색
물리적 상태
동결건조된 분말
BRN
1895465

안전

WGK 독일 3
RTECS 번호 MS3450700
F 고인화성물질 10-21
독성 LD50 intravenous in rat: 45mg/kg

히스톤유형VIII-S C화학적 특성, 용도, 생산

용도

Histone is suitable for use:
  • as a positive control in the in vitro kinase assay to examine the ability of Cdc2-cyclin B1 to phosphorylate GST-CD-4 protein
  • in Cdk5 activity assay
  • in histone H1 kinase assay
  • as a Poly(ADP-ribose) (PAR) acceptor in the assessment of in vitro PAR polymerase activity
  • as an acceptor of 32P from [γ-32P]ATP in order to measure protein kinase activity of lysate from small and large luteal cells

일반 설명

Histones are octameric proteins containing H3, H4, H2A and H2B. It is the core protein around which DNA is wound forming the nucleosome structure. The core histone proteins contain globular domains. Each protein is composed of basic amino acids at its N-terminal. The H2A has an extra amino acid at its C-terminal end forming a histone tail. The nucleosome structure is stabilized by the linker histones during chromatin condensation.

Biochem/physiol Actions

Histones are a group of proteins characterized by high levels of lysine and arginine that form reversible complexes with DNA. Based on the fractions, the molar mass of histones varies between 11-21kDa. Five different fractions have been isolated and characterized. They include H1 (lysine rich), H2a and H2b that are slightly lysine rich, H3 and H4 that are arginine rich. H1 acts as a link between "beads" (nu bodies) on the chromatin chain.

히스톤유형VIII-S 준비 용품 및 원자재

원자재

준비 용품


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