trilaciclib
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trilaciclib 속성
- 밀도
- 1.46±0.1 g/cm3(Predicted)
- 용해도
- H2O:15.0(Max Conc. mg/mL);33.59(Max Conc. mM)
- 산도 계수 (pKa)
- 13.33±0.20(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- White to yellow
안전
trilaciclib C화학적 특성, 용도, 생산
용도
Trilaciclib is indicated to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.상표명
CoselaTMSynthesis
The synthesis of trilaciclib is as follows:Intermediate 2 (21.1 g, 70 mmol) and 1-methyl-4-(6-aminopyridin-3-yl)piperazine (13.4 g, 70 mmol) were added to a 100 mL vacuum tube and reacted at 230° C. for 3 h.After the reaction, 300 mL of ethyl acetate was added, washed with water (120 mL) and saturated brine (120 mL) successively, dried with anhydrous sodium sulfate and filtered, the obtained solution was evaporated under reduced pressure to remove the solvent, and the obtained residue was recrystallized with ethanol, 27.5 g of Trilaciclib was obtained with a purity of 99% and a yield of 88%.
![synthesis of trilaciclib.png synthesis of trilaciclib.png](/NewsImg/2022-12-01/6380551047803772282782152.jpg)
저장
Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).trilaciclib 준비 용품 및 원자재
원자재
준비 용품
trilaciclib 공급 업체
글로벌( 71)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10312 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7513 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
sales@win-winchemical.com | China | 14278 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 |
sales@chemhifuture.com | China | 3136 | 58 |
Shanghai Huici Pharmaceutical Technology Co., LTD | +8618917134367 |
lixing@pharmahuici.com | China | 133 | 58 |
Shanghai Huici Pharmaceutical Technology Co., LTD | +8618917134367 |
lixing@pharmahuici.com | China | 133 | 58 |