Anti-BMP2A;ANTI-BMP-2;Anti-Bone Morphogenetic Protein 2;Monoclonal Anti-BMP2 antibody produced in mouse;ANTI-BONE MORPHOGENETIC PROTEIN 2 (BMP-2), HUMAN;Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper)
일반 설명
Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. Among the BMPs, BMP-2 has bone and cartilage inducing abilities. The other important functions of BMP-2 are in heart formation. BMP-2 signaling also involves active cross talk with major pathways such as Smad, MAPK, PI3K and NF-κ B.. Monoclonal Anti-BMP-2 recognizes recombinant BMP-2. It also detects BMP-4 (25% cross reactivity).
