7-클로로-1,2,3,4-테트라하이드로-벤조[B]아제핀-5-원
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7-클로로-1,2,3,4-테트라하이드로-벤조[B]아제핀-5-원 속성
- 녹는점
- 103.0 to 107.0 °C
- 끓는 점
- 356.5±41.0 °C(Predicted)
- 밀도
- 1.234±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C(protect from light)
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 2.36±0.20(Predicted)
- 색상
- 황백색에서 연한 노란색
- InChI
- InChI=1S/C10H10ClNO/c11-7-3-4-9-8(6-7)10(13)2-1-5-12-9/h3-4,6,12H,1-2,5H2
- InChIKey
- AHESNFIUAHTYGS-UHFFFAOYSA-N
- SMILES
- N1C2=CC=C(Cl)C=C2C(=O)CCC1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
그림문자(GHS): |
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유해·위험 문구: |
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예방조치문구: |
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7-클로로-1,2,3,4-테트라하이드로-벤조[B]아제핀-5-원 C화학적 특성, 용도, 생산
화학적 성질
White SolidSynthesis
The synthetic method of 7-Chloro-1,2,3,4-tetrahydrobenzo(b)azepin-5-one comprises the following steps: carrying out an acylation reaction between 4-chloroaniline and succinic anhydride to obtain 4-(4-chloroaniline)-4-oxobutyric acid; carrying out an intramolecular Friedel-Craft reaction on 4-(4-chloroaniline)-4-oxobutyric acid to obtain 7-chloro-3,4-tetrahydrobenzo[b]azepine-2,5-one; reacting 7-chloro-3,4-tetrahydrobenzo[b]azepine-2,5-one with ethylene glycol to obtain 7-chloro-3,4-tetrahydrobenzo[b]azepine-2-one-5-glycol ketal; reducing 7-chloro-3,4-tetrahydrobenzo[b]azepine-2-one-5-glycol ketal, and carrying out de-ketalation under an acidic condition to obtain 7-Chloro-1,2,3,4-tetrahydrobenzo(b)azepin-5-one.7-클로로-1,2,3,4-테트라하이드로-벤조[B]아제핀-5-원 준비 용품 및 원자재
원자재
준비 용품
7-클로로-1,2,3,4-테트라하이드로-벤조[B]아제핀-5-원 공급 업체
글로벌( 288)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Enki Biopharmaceuticals (Shanghai) Limited | +86-0086-2157680326 +8613916707528 |
yusu@enkibiopharma.com | China | 46 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16208 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21671 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9337 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29897 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2967 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
7-클로로-1,2,3,4-테트라하이드로-벤조[B]아제핀-5-원 관련 검색:
2-Methyl-4-nitrobenzoic acid
Tolvaptan Impurity 30
7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
Tolvaptan Impurity 17
Tolvaptan impurity 2
Tolvaptan Impurity 20
Tolvaptan Impurity 15
Tolvaptan Impurity 11
Tolvaptan Impurity 26
6-CHLORO-1H-BENZIMIDAZOLE
6-Chloro-2-benzoxazolethiol
5-Dehydro Tolvaptan
7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
1,2,3,4-Tetrahydro-benzo[b]azepin-5-one
2,3,4,5-Tetrahydro-1H-benzo[b]azepine
7-Chloro-1,2,3,4-tetrahydrobenzo(b)azepin-5-one
7-CHLORO-9-METHOXY-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE