리튬트리에틸보로하이드라이드용액
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리튬트리에틸보로하이드라이드용액 속성
- 녹는점
- 66-67° (Binger); mp 78-83° (dec) (Brown, 1977)
- 밀도
- 0.892 g/mL at 25 °C
- 인화점
- 1 °F
- 저장 조건
- Flammables + water-Freezer (-20°C)e area
- 용해도
- 테트라히드로푸란 및 벤젠과 혼합 가능.
- 물리적 상태
- 액체
- 색상
- 무색~밝은 회색
- 감도
- Air & Moisture Sensitive
- Merck
- 14,5544
- BRN
- 4151240
- 노출 한도
- ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
- CAS 데이터베이스
- 22560-16-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,C | ||
---|---|---|---|
위험 카페고리 넘버 | 11-14/15-19-34-40-37 | ||
안전지침서 | 16-26-33-36/37/39-43-45 | ||
유엔번호(UN No.) | UN 3399 4.3/PG 1 | ||
WGK 독일 | 1 | ||
F 고인화성물질 | 10-23 | ||
위험 등급 | 4.3 | ||
포장분류 | I | ||
HS 번호 | 29319090 | ||
기존화학 물질 | KE-22601 |
리튬트리에틸보로하이드라이드용액 C화학적 특성, 용도, 생산
개요
Lithium triethylborohydride is the organoboron compound with the formula LiEt3BH. Commonly referred to as LiTEBH or Superhydride, it is a powerful reducing agent used in organometallic and organic chemistry. It is a colorless or white liquid but is typically marketed and used as a THF solution. The related reducing agent sodium triethylborohydride is commercially available as toluene solutions.LiBHEt3 is a stronger reducing agent than lithium borohydride and lithium aluminium hydride.
화학적 성질
colorless to light grey cloudy solution용도
Powerful and selective reducing agent.As a reducing agentLithium triethylborohydride is used as a powerful reducing agent in organic synthesis for the conversion of carbonyl compounds to alcohols. It is also used in the preparation of alkynyl alcohols from the cleavage of cyclic keto-vinyl triflates. It is also used in the reduction of esters and lactones to alcohol and diol respectively. Further, it is used to prepare 1-methylcyclohexanol and 1,4-butanediol from 1,2-epoxybutane and gamma-butyrolactone respectively. It is also utilized for reductive cleavage of mesylates and tosylates in synthetic organic chemistry.
제조 방법
LiBHEt3 is prepared by the reaction of lithium hydride (LiH) and triethylborane (Et3B) in tetrahydrofuran (THF):LiH + Et3B → LiEt3BH
Its THF solutions are stable indefinitely in the absence of moisture and air.
주요 응용
Lithium Triethylborohydride (LiTEBH) is widely used as a powerful and selective reducing agent that shows super hydride activity in organic synthesis.LiTEBH can be used as a reagent:
To reduce alkyl halides to alkanes via dehydrogenation reactions.
For the selective reduction of epoxides to Markovnikov alcohols.
To reduce tosylates or mesylates primary alcohols to hydrocarbons.
For reductive cyclization reactions for the preparation of useful intermediates.
In the synthesis of hepta(manno-3-deoxy-6-O-t-butyldimethylsilyl)-β-cyclodextrin by reduction of hepta(manno-2,3-anhydro-6-O-t-butyldimethylsilyl)-β-cyclodextrin.
For hydrodefluorination of C-F bonds using Ni catalyst.
To prepare alkynyl alcohols from cleavage of cyclic keto-vinyl triflates.
In the stereoselective reduction of bicyclic imides, isoquinolines, and pyridines.
To prepare tungsten and molybdenum hydride complexes.
일반 설명
Super-Hydride? solution (Lithium triethylborohydride or LiTEBH) is widely used as a powerful and selective reducing agent that shows super hydride activity in organic synthesis.주의 사항
Moisture sensitive. Air sensitive. Incompatible with water and strong oxidizing agents.참고 문헌
Tamang, S.; Kim, K.; Choi, H.; Kim, Y.; Jeong, S. Synthesis of colloidal InSb nanocrystals via in situ activation of InCl3. Dalton Trans. 2015, 44 (38), 16923-16928.Kandapallil, B.; Colborn, R. E.; Bonitatibus, P. J.; Johnson, F. Synthesis of high magnetization Fe and FeCo nanoparticles by high temperature chemical reduction. J. Magn. Magn. Mater. 2015, 378, 535-538.
리튬트리에틸보로하이드라이드용액 준비 용품 및 원자재
원자재
준비 용품
리튬트리에틸보로하이드라이드용액 공급 업체
글로벌( 198)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21674 | 55 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29826 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34571 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9030 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
리튬트리에틸보로하이드라이드용액 관련 검색:
메틸트리메톡시실란 리튬트리메틸실일아세틸레이트 리튬 보로수소화물 리튬트리에틸보로하이드라이드용액 트리에틸보란 수소화리튬
SODIUM TRIETHYLBOROHYDRIDE
Triethylvinylsilane
Chlorotriethylsilane
TRIETHYLSILANOL
TRIETHYL(TRIFLUOROMETHYL)SILANE
Benzyltriethylammonium chloride
TRIETHYLGERMANIUM CHLORIDE
Potassium bis(trimethylsilyl)amide
ETHYNYLMAGNESIUM CHLORIDE
LITHIUM ISOPROPOXIDE
LITHIUM TETRACHLOROCUPRATE
Triethylsilane