6PPD-quinone

6PPD-quinone 구조식 이미지
카스 번호:
2754428-18-5
상품명:
6PPD-quinone
동의어(영문):
6PPD-Q;6PPD-quinone;Phentolamine Impurity 31;N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone;2-[(1,3-dimethylbutyl)amino]-5-(phenylamino)-2,5-cyclohexadiene-1,4-dione;2,5-Cyclohexadiene-1,4-dione, 2-[(1,3-dimethylbutyl)amino]-5-(phenylamino)-;2-((4-methylpentan-2-yl)amino)-5-(phenylamino)cyclohexa-2,5-diene-1,4-dione;2- ((4-methylpent-2-yl) amino) -5- (phenylamino) cyclohex-2,5-diene-1,4-dione
CBNumber:
CB810899610
분자식:
C18H22N2O2
포뮬러 무게:
298.38
MOL 파일:
2754428-18-5.mol

6PPD-quinone 속성

끓는 점
442.2±45.0 °C(Predicted)
밀도
1.12±0.1 g/cm3(Predicted)
용해도
아세토니트릴(약간), 클로로포름(약간), 아세트산에틸(약간)에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
0.61±0.20(Predicted)
색상
진한 주황색에서 진한 빨간색까지
InChI
InChI=1S/C18H22N2O2/c1-12(2)9-13(3)19-15-10-18(22)16(11-17(15)21)20-14-7-5-4-6-8-14/h4-8,10-13,19-20H,9H2,1-3H3
InChIKey
UBMGKRIXKUIXFQ-UHFFFAOYSA-N
SMILES
C1(=O)C=C(NC2=CC=CC=C2)C(=O)C=C1NC(C)CC(C)C

안전

6PPD-quinone C화학적 특성, 용도, 생산

개요

6PPD-quinone is an oxidized derivative of the tire antiozonant and substituted p-phenylenediamine 6-PPD. It is toxic to rainbow trout (O. mykiss) and brook trout (S. fontinalis; LC50s = 0.59 and 1.96 μg/L, respectively) but not to arctic char (S. alpinus) and white sturgeon (A. transmontanus; LC50s = >12.7 μg/L for both). 6PPD-quinone (10 μg/L) induces cell death and germline DNA damage and decreases the number of mitotic cells in C. elegans gonads. Urine levels of 6-PPD-quinone are increased in pregnant women compared to non-pregnant adults and children.

Safety

6PPD-quinone (6PPD-q) is an oxidation product of the antioxidant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) present in rubber. Studies have shown that 6PPD and 6PPD- q are also present in human urine, including adults, children, and pregnant women, and that urinary 6PPD- q concentrations were significantly higher than 6PPD; pregnant women had significantly higher concentrations of 6PPD and 6PPD- q (median 0.068 and 2.91 ng/mL, respectively) than adults (0.018 and 0.40 ng/mL) and children (0.015 and 0.076 ng/mL). The high daily urinary excretion of 6PPD-Q in pregnant women was estimated to be 273 (ng/kg bw)/day. 6PPD-Q is a lethal toxicant to a wide range of aquatic species, and its potential risk to human health from long-term exposure requires urgent attention.

6PPD-quinone 준비 용품 및 원자재

원자재

준비 용품


6PPD-quinone 공급 업체

글로벌( 30)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139
orders@jknbiochem.com China 4692 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 12898 58
Zhengzhou Anhuida Chemical Co., Ltd
+8615903659408
admin@ahdchem.com China 298 58
Meike meditech (Foshan) Co.,Ltd
+86-0757-22239986 +86-18029359586
sales@mkmeditech.com China 1134 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203
info@chemextension.com China 42057 58
Zhengzhou Huiju Chemical Co., Ltd. 0371-55900031 18137872243
2853979815@qq.com China 10002 55
Shanghai Chemilab Biotechnology CO.,Ltd 18116465878
kmlb@kaimilaibo.com China 2401 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 13720134139
orders@jknbiochem.com China 5316 58
Hefei Chengquan Biotechnology Co., Ltd 0551-18956023141 18956023141
402974597@qq.com China 118 58

Copyright 2019 © ChemicalBook. All rights reserved