디브롬프로파미딘

디브롬프로파미딘 C화학적 특성, 용도, 생산

Originator

Dibrompropamidine,Aventis Pharma AS

Manufacturing Process

2,2’-Dibromo-4,4’-dicyano-α,γ-diphenoxypropane (3.0 g) and anhydrous ethanol (3.0 ml) were dissolved in anhydrous chloroform (40 ml). The solution was saturated at 0°C with dry hydrogen chloride and set aside for 7 day. The iminoether hydrochloride which crystallised out, was filtered off and washed with light petroleum. The solid was added to 12% ammoniacal ethanol (47 c.c.) and the mixture was heated at 60°C for 6 hours. Solution was obtained after 3 hours and the amidine hydrochloride began to cryistallise. The mixture was ice-cooled, and the white crystalline solid was filtered off, washed with 2 N hydrochloric acid, and recrystallised twice from 0.5 N hydrochloric acid.
2,2'-Dibromo-4,4'-diamidino-α,γ-diphenoxypropane dihydrochloride (2.1 g) [another name: 4,4'-(Trimethylenedioxy)bis(3-bromobenzamidine)] separated as white prisme. Melting point 309°C. (decomp.).
Berg S.S., GB Patent No. 598,911; March 22, 1945; Assigned to May and Bakker Limited, a British Co., Dagenham, Essecs.

Therapeutic Function

Antiprotozoal

디브롬프로파미딘 준비 용품 및 원자재

원자재

준비 용품

디브롬프로파미딘 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1991	58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd	18162595016	3287908757@qq.com	China	9131	58

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