Flunoxaprofen

Flunoxaprofen 구조식 이미지
카스 번호:
66934-18-7
상품명:
Flunoxaprofen
동의어(영문):
Priaxim;Flunoxaprofen;S-(+)-Flunoxaprofen;Flunoxaprofen USP/EP/BP;(S)-2-(4-Fluorophenyl)-α-methyl-5-benzoxazoleacetic acid;5-Benzoxazoleacetic acid, 2-(4-fluorophenyl)-α-methyl-, (αS)-
CBNumber:
CB81178784
분자식:
C16H12FNO3
포뮬러 무게:
285.273
MOL 파일:
66934-18-7.mol

Flunoxaprofen 속성

녹는점
162-164°
알파
D20 +50° (c = 2% in DMF)
끓는 점
419.4±30.0 °C(Predicted)
밀도
1.334±0.06 g/cm3(Predicted)
산도 계수 (pKa)
4.36±0.30(Predicted)

안전

독성 LD50 orally in mice: ~1200 mg/kg (Dunwell)

Flunoxaprofen C화학적 특성, 용도, 생산

개요

Flunoxaprofen is an antiinflammatory related to now withdrawn benoxaprofen, reportedly useful in the treatment of rheumatoid arthritis, myositis, synovitis and osteoarthritis. Its major mechanism of action is reported to be lipoxygenase inhibition, thus enabling the control of inflammation with less severe gastric disturbances.

정의

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group (the S-enantiomer). Although it was shown to be effective in treatment of rheumatoid arthritis and osteoarthritis, the clinical use of flunoxaprofen was discontinued due to possible hepatotoxic side-effects.

Flunoxaprofen 준비 용품 및 원자재

원자재

준비 용품


Flunoxaprofen 공급 업체

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