Prazosin
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Prazosin 속성
- 녹는점
- 278-280°C
- 끓는 점
- 510.33°C (rough estimate)
- 밀도
- 1.3275 (rough estimate)
- 굴절률
- 1.7600 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨, 가열)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- pKa 6.54(50% EtOH) (Uncertain)
- 색상
- 흰색에서 황백색까지
- 수용성
- 3.2mg/L(22.5℃)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Prazosin C화학적 특성, 용도, 생산
용도
Prazosin is used for treating mid-to-moderate hypertension. When using this drug, blood pressure is reduced without any significant change in indicators of cardiac function such as frequency, coronary flow, or cardiac output.정의
ChEBI: A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.Clinical Use
Prazosin is effective in reducing all grades of hypertension. The drug can be administered alone in mild and (in some instances) moderate hypertension.When the hypertension is moderate or severe, prazosin generally is given in combination with a thiazide diuretic and a -blocker. The antihypertensive actions of prazosin are considerably potentiated by coadministration of thiazides or other types of antihypertensive drugs.Prazosin may be particularly useful when patients cannot tolerate other classes of antihypertensive drugs or when blood pressure is not well controlled by other drugs. Since prazosin does not significantly influence blood uric acid or glucose levels, it can be used in hypertensive patients whose condition is complicated by diabetes mellitus or gout. Prazosin and other -antagonists find use in the management of benign prostatic obstruction, especially in patients who are not candidates for surgery. Blockade of -adrenoceptors in the base of the bladder and in the prostate apparently reduces the symptoms of obstruction and the urinary urgency that occurs at night.
부작용
Although less of a problem than with phenoxybenzamine or phentolamine, symptoms of postural hypotension, such as dizziness and light-headedness, are the most commonly reported side effects associated with prazosin therapy. These effects occur most frequently during initial treatment and when the dosage is sharply increased. Postural hypotension seems to be more pronounced during Na deficiency, as may occur in patients on a low-salt diet or being treated with diuretics, - blockers, or both.Prazosin 준비 용품 및 원자재
원자재
1-(2-푸로일)피레라진
벤조니트릴
Ammonia-ammonium chloride
요오드 메탄
티오요소
암모니아(가스)
2-Furoyl chloride
2-Chloro-4-amino-6,7-dimethoxyquinazoline
피페라진
2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
준비 용품
Prazosin 공급 업체
글로벌( 130)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29810 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10319 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6312 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 7724 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 |
gksales1@gk-bio.com | China | 9312 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | |
ada@sh-teruiop.com | China | 875 | 58 |
sgtlifesciences pvt ltd | +8617013299288 |
dj@sgtlifesciences.com | China | 12373 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
Prazosin 관련 검색:
트리스(하이드록시메틸)아미노메탄 디메톡시메탄 1,1-디메톡시에탄 다이메톡시다이페닐 실레인 디메톡시디메틸실란 글리신 6-아미노 카프로산 3-아미노페놀
ALTRENOGEST
2-BROMO-1-(3,5-DIHYDROXYPHENYL)ETHANONE
1-(3,5-Dihydroxyphenyl)-2-[(1,1-diMethylethyl)(phenylMethyl)aMino]ethanone HydrobroMide
3,5-Dihydroxybenzoic acid
Trimazosin
PRAZOSIN HYDROCHLORIDE USP,PRAZOSIN HYDROCHLORIDE PERIPHERAL A1 ADR ENER,Prazosin HCl USP,PRAZOSIN HYDROCHLORIDE,PRAZOSIN HCL
5-NITROURACIL/PRAZOSIN DOXAZOSIN
Quinazoline
Prazosin
AMINO ACIDS