ChemicalBook >제품 카탈로그 >(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid 구조식 이미지

카스 번호:: 136696-10-1

상품명:: (5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid

동의어(영문):: 12-Oxo-ltb4;12-oxoleukotriene B4;12-Keto-leukotriene B4;12-dehydro-leukotriene B4;SJVWVCVZWMJXOK-NOJHDUNKSA-N;(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid;6,8,10,14-Eicosatetraenoic acid, 5-hydroxy-12-oxo-, (S-(E,Z,E,Z))-;6,8,10,14-Eicosatetraenoic acid, 5-hydroxy-12-oxo-, (5S,6Z,8E,10E,14Z)-

CBNumber:: CB81235331

분자식:: C20H30O4

포뮬러 무게:: 334.45

MOL 파일:: 136696-10-1.mol

속성

안전

용도

공급 업체 8

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid 속성

끓는 점: 524.2±50.0 °C(Predicted)

밀도: 1.036±0.06 g/cm3(Predicted)

저장 조건: Store at -80°C,protect from light

용해도: DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): > 1 mg/ml

산도 계수 (pKa): 4.66±0.10(Predicted)

안전

위험 및 안전 성명

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드

예방조치문구:

NFPA 704

	3
2		0

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid C화학적 특성, 용도, 생산

개요

Leukotriene B₄ (LTB₄) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. 12-oxo LTB₄ is an initial metabolite of LTB₄ formed via the LTB₄ 12-hydroxydehydrogenase pathway. It is rapidly converted to 10,11-dihydro-12-oxo-LTB₄, followed by reduction of the 12-oxo group to give 10,11-dihydro-LTB₄. 12-oxo-LTB₄ (EC₅₀ = 33 nM) is about 70-fold less potent than LTB₄ (EC₅₀ = 0.46 nM) at stimulating Ca²⁺ mobilization in human neutrophils. It is also significantly less potent than LTB₄ at stimulating neutrophil migration with EC₅₀ values of 170 and 2.7 nM for 12-oxo-LTB₄ and LTB₄, respectively.

정의

ChEBI: A long-chain fatty acid consisting of leukotriene B4 having a 12-keto group in place of the 12-hydroxy group.

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid 준비 용품 및 원자재

원자재

준비 용품

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid 공급 업체

글로벌( 8)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7984	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid 관련 검색:

(5S,6Z,8E,10E,14Z)-5-hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid 2,4-HEPTADIEN-6-ONE