루브라톡시나

루브라톡시나
루브라톡시나 구조식 이미지
카스 번호:
22467-31-8
한글명:
루브라톡시나
동의어(한글):
루브라톡시나
상품명:
RUBRATOXINA
동의어(영문):
RUBRATOXINA;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
CBNumber:
CB81405198
분자식:
C26H32O11
포뮬러 무게:
520.528
MOL 파일:
22467-31-8.mol

루브라톡시나 속성

녹는점
210-214℃ (decomposition)
저장 조건
Store at -20°C
용해도
Acetonitrile: soluble; DMSO: soluble
물리적 상태
분말
색상
하얀색
안전
  • 위험 및 안전 성명
유해 물질 데이터 22467-31-8(Hazardous Substances Data)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
2 0

루브라톡시나 C화학적 특성, 용도, 생산

개요

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

용도

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

루브라톡시나 준비 용품 및 원자재

원자재

준비 용품


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