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이바틴

이바틴 구조식 이미지

카스 번호:: 745046-84-8

한글명:: 이바틴

동의어(한글):: 이바틴

상품명:: IVACHTIN

동의어(영문):: IVACHTIN;2-(4-methyl-8-morpholin-4-ylsulfonyl-1,3-dioxopyrrolo[3,4-c]quinolin-2-yl)ethyl acetate;1H-Pyrrolo[3,4-c]quinoline-1,3(2H)-dione, 2-[2-(acetyloxy)ethyl]-4-methyl-8-(4-morpholinylsulfonyl)-;2-(4-Methyl-8-(morpholinosulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl)ethyl acetate;2-[4-Methyl-8-(morpholin-4-ylsulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl]ethylacetate;modest,reversibl,Inhibitor,noncompetitive,Caspase,caspases,nonpeptide,inhibit,apoptosis,Ivachtin,selectivity,staurosporininduced

CBNumber:: CB82459565

분자식:: C20H21N3O7S

포뮬러 무게:: 447.46

MOL 파일:: 745046-84-8.mol

속성

안전

용도

공급 업체 56

이바틴 속성

끓는 점: 665.0±65.0 °C(Predicted)

밀도: 1.459±0.06 g/cm3(Predicted)

저장 조건: Desiccate at +4°C

용해도: Limited solubility, soluble in DMSO or DMF

산도 계수 (pKa): 1.87±0.20(Predicted)

물리적 상태: 회백색 고체

안전

이바틴 C화학적 특성, 용도, 생산

용도

Ivachtin is a potent, cell-permeable, reversible, non-competitive inhibitor of caspase-3.

일반 설명

A cell-permeable, non-peptidyl pyrroloquinoline compound that acts as a potent, reversible, and non-competitive inhibitor of caspase-3 (IC₅₀ = 23 nM) with larger than 10-fold greater selectivity towards caspase-3 than caspases-1, -2, and -4 through -10. Shown to display higher anti-apoptotic activity than Z-VAD-FMK (Cat. No. 627610) in preventing Staurosporine- (Cat. No. 569397) induced apoptosis in human Jurkat T cells.

Biochem/physiol Actions

Cell permeable: yes

이바틴 준비 용품 및 원자재

원자재

준비 용품

이바틴 공급 업체

글로벌( 56)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2782	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 18892239720	psaitong@jm-bio.com	China	12306	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1990	58

이바틴 관련 검색:

4-METHYL-2,3-DIHYDRO-1H-PYRROLO[3,4-C]QUINOLINE-1,3-DIONE 2,4-DIMETHYLQUINOLINE-3-CARBOXAMIDE N-[2-(ACETOXY)ETHYL]-3-PYRIDINECARBOXAMIDE IVACHTIN