9,10-디히드로-6-메틸-에르골린-8-카르복실산
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9,10-디히드로-6-메틸-에르골린-8-카르복실산 속성
- 녹는점
- >170°C (dec.)
- 알파
- D20 +40° (c = 0.5 in pyridine)
- 끓는 점
- 411.48°C (rough estimate)
- 밀도
- 1.1028 (rough estimate)
- 증기압
- 0Pa at 20℃
- 굴절률
- 1.6240 (estimate)
- 저장 조건
- Controlled Substance, -20°C Freezer
- 산도 계수 (pKa)
- 3.44, 7.68(at 25℃)
- 수용성
- 267mg/L at 20℃
- LogP
- -0.7 at 20℃
안전
| HS 번호 | 29396300 | ||
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| DEA Controlled Substances | CSCN: 7300 CSA SCH: Schedule III NARC: No |
9,10-디히드로-6-메틸-에르골린-8-카르복실산 C화학적 특성, 용도, 생산
개요
A precursor of the semisynthetic ergot derivatives, but having no biological activity itself. It is subject to controls under the Controlled Substances Act of 1970 in the United States, since it is the immediate precursor for the synthesis of LSD. Lysergic acid is obtained by hydrolysis of ergot alkaloids, either obtained from grains infected with Claviceps or, more commonly, by fermentation in submerged culture.화학적 성질
beige to brown powder용도
Labelled Lysergic acid. Lysergic acid and iso-lysergic acid are the main cleavage products formed on alkaline hydrolysis of the alkaloids which are characteristic of ergot. Potent hallucinogen; non-selective serotonin receptor agonist. Controlled substanc정의
ChEBI: An ergoline alkaloid comprising 6-methylergoline having additional unsaturation at the 9,10-position and a carboxy group at the 8-position.Purification Methods
It crystallises from water as a hydrate. The methyl ester crystallises from C6H6 and has m 168o; the amide [478-94-4] has m 242o(dec) (from MeOH) and []546 +15o (c 0.5, pyridine).The (-)-hydrochloride has m 208-210o(dec, from MeOH). [Kornfeld et al. J Am Chem Soc 7 6 5256 1954,Kornfeld et al. J Am Chem Soc 78 3087 1956, Beilstein 25 III/IV 934,]9,10-디히드로-6-메틸-에르골린-8-카르복실산 준비 용품 및 원자재
원자재
Formamide, N-[(9,10-didehydro-6-methylergolin-8-ylidene)[(4-methylphenyl)sulfonyl]methyl]-
Benz[cd]indol-5(1H)-one, 4-bromo-3,4-dihydro-
Benz[cd]indol-5(1H)-one, 3,4-dihydro-4-[methyl(2-oxopropyl)amino]-
Benz[cd]indol-5(1H)-one, 3,4-dihydro-4-[methyl[(2-methyl-1,3-dioxolan-2-yl)methyl]amino]-
Benz[cd]indol-5(1H)-one, 1-(2,2-dimethyl-1-oxopropyl)-3,4-dihydro-4-[methyl[(2-methyl-1,3-dioxolan-2-yl)methyl]amino]-
Ergolin-8-one, 9,10-didehydro-6-methyl-
Ergoline-8-carboxylic acid, 9,10-didehydro-6-methyl-, methyl ester
Ergolin-8-one, 9,10-didehydro-6-methyl-, (±)-
Benz[cd]indol-5(1H)-one, 4-bromo-1-(2,2-dimethyl-1-oxopropyl)-3,4-dihydro-