Tazemetostat (EPZ-6438)
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Tazemetostat (EPZ-6438) 속성
- 녹는점
- >162°C (dec.)
- 끓는 점
- 750.8±60.0 °C(Predicted)
- 밀도
- 1.163±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- DMSO에 용해됩니다(최대 25mg/ml).
- 산도 계수 (pKa)
- 11.92±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 회백색
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 최대 1개월 동안 -20°에서 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Tazemetostat (EPZ-6438) C화학적 특성, 용도, 생산
용도
EPZ 6438 is a potent and selective inhibitor of EZH2.생물학적 활성
Tazemetostat (EPZ-6438) is a potent, and selective EZH2 inhibitor with K i and IC50 of 2.5 nM and 11 nM in cell-free assays, exhibiting a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMT.target
EZH2(Cell-free assay)Tazemetostat (EPZ-6438) 준비 용품 및 원자재
원자재
BenzaMide, 5-broMo-N-[(1,2-dihydro-4,6-diMethyl-2-oxo-3-pyridinyl)Methyl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-
Benzoic acid, 5-broMo-2-Methyl-3-[(tetrahydro-2H-pyran-4-yl)aMino]-, Methyl ester
3-(아미노메틸)-4,6-디메틸-1,2-디히드로피리딘-2-온히드로클로라이드
메틸3-아미노-5-브로모-2-메틸벤조에이트
5-BROMO-2-METHYL-3-NITROPHENYL METHYLCARBOXYLATE
4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZYL]MORPHOLINE
Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-, Methyl ester
5-BROMO-2-METHYL-3-NITROBENZOIC ACID
Benzoic acid, 5-broMo-3-[ethyl(tetrahydro-2H-pyran-4-yl)aMino]-2-Methyl-
준비 용품
Tazemetostat (EPZ-6438) 공급 업체
글로벌( 191)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12449 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 973 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29891 | 58 |
TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 |
sales@tianpharm.com | CHINA | 304 | 58 |
Hainan Xiyuan Chemical Technology Co., Ltd. | +86-15008981366 |
15008981366@163.com | CHINA | 9 | 58 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Tazemetostat (EPZ-6438) 관련 검색:
GDC-0032
tasquinimod
GDC-0084
SH-4-54
Osimertinib mesylate
Niraparib
Mertansine
(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Enasidenib
Ivosidenib
ABBV-075
Ponatinib
Selonsertib
Panobinostat
GSK 343
(2R,3R,4S,5R)-2-(6-aMino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]iMidazol-2-yl)ethyl)cyclobutyl)(isopropyl)aMino)Methyl)tetrahydrofuran-3,4-diol
MM-102
UNC 1999