2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide

2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide 구조식 이미지
카스 번호:
107522-19-0
상품명:
2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide
동의어(영문):
PDE7-IN-2;2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide;N-[2-(5-chloro-2-nitrophenylthio)phenyl]acetamide;Acetamide, N-[2-[(5-chloro-2-nitrophenyl)thio]phenyl]-;2 Acetamidophenyl 5 chloro 2 nitrophenyl sulfide,2Acetamidophenyl 5chloro2nitrophenyl sulfide
CBNumber:
CB83152463
분자식:
C14H11ClN2O3S
포뮬러 무게:
322.77
MOL 파일:
107522-19-0.mol

2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide 속성

끓는 점
494.3±45.0 °C(Predicted)
밀도
1.44±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
14.40±0.70(Predicted)

안전

2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide C화학적 특성, 용도, 생산

개요

2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide is a sulfide-like inhibitor of phosphodiesterase 7 (PDE7; IC50 = 2.1 μM). It is selective for PDE7A, producing only 10-11% inhibition of PDE3A, PDE4D, and PDE4B at 10 μM. It also has no antioxidant activity or inhibitory activity against a panel of protein kinases. Sulfide-like PDE7 inhibitors derived from 2-acetamidophenyl 5-chloro-2-nitrophenyl sulfide have cytoprotective and anti-inflammatory effects on SH-SY5Y neuroblastoma cells without action in a surrogate emesis mouse model.

2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide 준비 용품 및 원자재

원자재

준비 용품


2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide 공급 업체

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TargetMol Chemicals Inc.
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BOC Sciences 16314854226
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
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TargetMol Chemicals Inc. 4008200310
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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
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