ACETYLSHIKONIN
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ACETYLSHIKONIN 속성
- 녹는점
- 86°C
- 끓는 점
- 553.2±50.0 °C(Predicted)
- 밀도
- 1.326±0.06 g/cm3(Predicted)
- 저장 조건
- 4°C, protect from light
- 용해도
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 7.12±0.20(Predicted)
- 색상
- Brown to khaki
- 안정성
- 흡습성
- LogP
- 2.700 (est)
- CAS 데이터베이스
- 24502-78-1(CAS DataBase Reference)
안전
| 위험 카페고리 넘버 | 36/37/38 | ||
|---|---|---|---|
| 안전지침서 | 26-36/37/39 | ||
| 독성 | mouse,LD50,intraperitoneal,41mg/kg (41mg/kg),BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)BEHAVIORAL: ATAXIA,Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 73, Pg. 193, 1977. |
ACETYLSHIKONIN C화학적 특성, 용도, 생산
화학적 성질
Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma.생물학적 활성
Acetylshikonin is one naphthoquinone derivative isolated from the Lithospermum erythrorhizon, exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors.Acetylshikonin inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated.
Certain shikonin derivatives(such as Acetyl shikonin) act as modulators of the Nur77-mediated apoptotic pathway and identify a new shikonin-based lead that targets Nur77 for apoptosis induction.
Acetylshikonin, shikonin, and alkannin have accelerative effect on the proliferation of granulation tissue in rats.
Acetylshikonin isolated from Arnebia euchroma (Royle) Johnst cell suspension cultures exhibits specific in vivo and in vitro antitumor effects.
Acetylshikonin has inhibitory effect on the edematous response is due neither to the release of steroid hormones from the adrenal gland nor to the glucocorticoid activity, but probably partly to the suppression of mast cell degranulation and partly to protection of the vasculature from mediator challenge.
Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress.
ACETYLSHIKONIN 준비 용품 및 원자재
원자재
준비 용품
ACETYLSHIKONIN 공급 업체
글로벌( 171)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29900 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 |
marketing1@neostarunited.com | China | 12210 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 |
sales@chemnorm.com | CHINA | 2935 | 58 |
ACETYLSHIKONIN 관련 검색:
캠퍼롤
Atractylodin
Neohesperidosyl dihydrochalcone
Myricetin
Diosgenin
Bengenin
Isorhamnetin
Taxifolin
ARTEMISININ
PINOCEMBRIN
Alkannin
5,8-Dihydroxy-1,4-naphthoquinone
ISOVALERYLSHIKONIN
ISOBUTYRYLSHIKONIN
(BETA,BETA-DIMETHYLACRYL)SHIKONIN
ACETYLSHIKONIN
(2-METHYL-N-BUTYRYL)SHIKONIN
BETA-HYDROXYISOVALERYLSHIKONIN