DFMO

DFMO 구조식 이미지
카스 번호:
70052-12-9
상품명:
DFMO
동의어(영문):
DIFLUOROMETHYLORNITHINE;DFMO;RFI 71782;Ccris 3295;Brn 2250529;EFLORNITINE;DL-EFLORNITHINE;H-DL-(F2ME)ORN-OH;α-Difluoromethylornitine;α-difluoromethylornithine
CBNumber:
CB8373227
분자식:
C6H12F2N2O2
포뮬러 무게:
182.17
MOL 파일:
70052-12-9.mol
MSDS 파일:
SDS

DFMO 속성

녹는점
138 °C
끓는 점
347.0±42.0 °C(Predicted)
밀도
1.1800 (estimate)
저장 조건
Store at 0°C
용해도
H2O: >10 mg/mL, 가용성
산도 계수 (pKa)
1.22±0.44(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
하얀색

안전

WGK 독일 3
유해 물질 데이터 70052-12-9(Hazardous Substances Data)

DFMO C화학적 특성, 용도, 생산

화학적 성질

Off-white powder

용도

DL-α-Difluoromethylornithine hydrochloride hydrate has been used to reduce the effects of arginine on cell proliferation. It has also been used to investigate the effect of bisphenol A (BPA) on the migration of an established ovine trophectoderm (oTr1) cell line.

일반 설명

Difluoromethylornithine is a?fluorinated ornithine analog, which acts as a rate-limiting enzyme of polyamine biosynthesis. It is used to treat female facial hirsutism and human African trypanosomiasis. Difluoromethylornithine functions as a chemopreventive and chemotherapeutic agent against neuroblastoma and colorectal cancer. It exhibits cytostatic?effects on mammalian cells and tissues.

생물학적 활성

Inhibitor of ornithine decarboxylase that inhibits polyamine biosynthesis. Displays antiapoptotic, antiangiogenic and antiparasitic activity.

DFMO 준비 용품 및 원자재

원자재

준비 용품


DFMO 공급 업체

글로벌( 66)공급 업체
공급자 전화 이메일 국가 제품 수 이점
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19743 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763
sales@tnjchem.com China 25363 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131980 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2127 70
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
China 1494 55

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