CCG-232601
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CCG-232601 속성
- 끓는 점
- 683.1±55.0 °C(Predicted)
- 밀도
- 1.39±0.1 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 13.69±0.70(Predicted)
안전
CCG-232601 C화학적 특성, 용도, 생산
개요
CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971 . CCG-232601 inhibits MRTF-dependent transcription in HEK293T cells (IC50 = 0.55 μM in a luciferase reporter assay). It also reduces expression of α-smooth muscle actin (α-SMA) in TGF-β-stimulated human dermal fibroblasts to 31% of control when used at a concentration of 10 μM. CCG-232601 (50 mg/kg) inhibits increases in dermal thickness and hydroxyproline content in a mouse model of dermal fibrosis induced by bleomycin .CCG-232601 준비 용품 및 원자재
원자재
준비 용품
CCG-232601 공급 업체
글로벌( 11)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32038 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14055 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11217 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 |
15151849396@163.com | China | 999 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24649 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 |
sales@tybiochem.com | China | 7413 | 58 |
| RD International Technology Co., Limited | 18024082417 |
market@ubiochem.com | China | 9272 | 58 |