2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide 구조식 이미지
카스 번호:
1817798-20-1
상품명:
2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide
동의어(영문):
Atorvastatin Impurity 159;Atorvastatin calcium impurity 80;3-Fluoro-a-(2-methyl-1-oxopropyl)--oxo-N,-diphenyl-benzenebutanamide;3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide;3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide;Benzenebutanamide, 3-fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-;2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide
CBNumber:
CB84845434
분자식:
C26H24FNO3
포뮬러 무게:
417.4720632
MOL 파일:
1817798-20-1.mol

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide 속성

끓는 점
631.4±55.0 °C(Predicted)
밀도
1.211±0.06 g/cm3(Predicted)
저장 조건
Room Temperature
용해도
클로로포름, 디클로로메탄, 디메틸술폭시드, 메탄올에 용해됨
산도 계수 (pKa)
11.49±0.59(Predicted)

안전

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide C화학적 특성, 용도, 생산

용도

3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide is an intermediate in the synthesis of 3-Fluoro Atorvastatin Sodium Salt (F587915). 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide 준비 용품 및 원자재

원자재

준비 용품


2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide 공급 업체

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