Obiltoxaximab

Obiltoxaximab C화학적 특성, 용도, 생산

효소 저해제

This anti-anthrax therapeutic (MW = 145.5 kDa; CAS 1351337-07-9; Trade Name = Anthim?) is an FDA-approved mouse/human chimeric monoclonal antibody that binds to protective antigen (Kd = 0.3 nM), blocking the latter’s interaction with host cell anthrax receptor, which mediates the translocation of lethal factor [LF] and edema factor into the host cell cytoplasm (See Anthrax Lethal Toxin). Anthim is recommended for the treatment (when combined with antibacterial drugs, such as levofloxacin, ciprofloxacin and doxycycline) and prophylactically (when used alone) treat inhalational anthrax (i.e., exposure to Bacillus anthracis spores. Obiltoxaximab was been designed to neutralize the free protective antigen of B. anthracis, thereby inhibiting the lethal effects of anthrax toxins. Inasmuch as it would be unethical to conduct clinical trials in humans with clinically inducced inhalational anthrax, Anthim’s efficacy was evaluated in NZW rabbits and cynomolgus macaques. See also JMV 390-1

Obiltoxaximab 준비 용품 및 원자재

원자재

준비 용품

Obiltoxaximab 공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
ShangHai Biochempartner Co.,Ltd	177-54423994 17754423994	2853530910@QQ.com	China	8014	62
Guangzhou Hongyuan Chemical Co.,Ltd	15817493340	981810490@qq.com	China	1565	58
Wuhan Chemstan Biotechnology Co., Ltd.	027-65317797 15926423062	422450190@qq.com	China	10351	58
Biolab Reagents	027-65279366 18162686757	products@biolabreagent.com	China	9818	58
Wuhan Jingkangen Biomedical Technology Co., Ltd	13720134139 13720134139	orders@jknbiochem.com	China	5792	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
Changsha Fuzhen Biotechnology Co.，LTD	13823398779 18670069958	313359644@qq.com	China	3263	58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	17316404525	209533805@qq.com	China	9787	58
Wanxin Biotechnology (Jiaxing) Co., LTD	0573-83568680 18057391398	3956524501@qq.com	China	1440	58