PIVMECILLINAM

PIVMECILLINAM 구조식 이미지
카스 번호:
32886-97-8
상품명:
PIVMECILLINAM
동의어(영문):
PIVMECILLINAM;PIVAMDINOCILLIN;AMDINOCILLIN PIVOXIL;PIVMECILLINAM USP/EP/BP;[(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(1-azepanylmethylene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2S,5β)-6α-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid [2,2-dimethyl-1-oxopropoxy]methyl ester;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)-;PIVMECILLINAM IMPURITY CMETHYLENE 2,2-DIMETHYLPROPANOATE (2RS,4S)-2-[[[(HEXAHYDO-1H-AZEPIN-1-YL)METHYLENE]AMINO]METHYL]-5,5-DIMETHYLTHIAZOLIDIN-4-CARBOXYLATE EPP(CRM STANDARD)
CBNumber:
CB8680680
분자식:
C21H33N3O5S
포뮬러 무게:
439.57
MOL 파일:
32886-97-8.mol

PIVMECILLINAM 속성

녹는점
118-119 C
알파
D20 +231° (c = 1 in 96% ethanol)
끓는 점
581.0±60.0 °C(Predicted)
밀도
1.30±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO: 용해성5mg/mL, 투명(가온)
물리적 상태
가루
산도 계수 (pKa)
8.11±0.60(Predicted)
색상
흰색에서 베이지색
optical activity
[α]/D +215 to +245°, c = 1 in ethanol

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-37/39
WGK 독일 3
RTECS 번호 XI0185000
독성 LD50 in mice, rats (mg/kg): 475-480, 465 i.v.; 1736-1930, 1935-2100 s.c.; 3020, 9500-10000 orally (Sato)

PIVMECILLINAM C화학적 특성, 용도, 생산

개요

Pivmecillinam was found by a series of studies at Leo in 1969. It is a derivative of 6βformamidinopenicillanic acid and shows strong activity against gram-negative bacilli. Pivmecillinam is hydrolyzed by intestinal esterase and acts similarly to mecillinam after oral administration. Mecillinam shows weaker activity than ampicillin against gram-positive cocci but much stronger activity against a wide range of gramnegative bacilli.

용도

Antibacterial.

PIVMECILLINAM 준비 용품 및 원자재

원자재

준비 용품


PIVMECILLINAM 공급 업체

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