Azasetron hydrochloride
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Azasetron hydrochloride 속성
- 녹는점
- 281° (dec); mp 305° (dec) (Kawakita)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 메탄올(약간 용해됨), 물(약간 용해됨)
- 물리적 상태
- 백색 고체.
- 색상
- 하얀색
- CAS 데이터베이스
- 123040-16-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
독성 | LD50 in male, female rats (mg/kg): 135, 132 i.v. (Takagi) |
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그림문자(GHS): |
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신호 어: | Warning | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Azasetron hydrochloride C화학적 특성, 용도, 생산
개요
Nazasetron (azasetron) hydrochloride is the fourth in the class of highly potent 5- HT3 receptor antagonists to reach the market for prophylaxis of severe nausea and vomiting induced by cytotoxic chemotherapy and by total body X-radiation. In a study with 146 cancer patients suffering from emesis induced by cisplatin, nazasetron was reported to be markedly effective in 72% of subjects. Nazasetron is devoid of dopamine D2 receptor blocking activity and therefore is free of the extrapyrimidal side effects associated with other commonly used antiemetics such as metoclopramide and domperidone. Nazasetron has been reported to be potentially useful for the treatment of gastrointestinal motility dysfunction, such as gastric stasis, vomiting and irritable bowel syndrome.화학적 성질
White to Off-White Solid용도
Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.생물학적 활성
A selective and potent 5-HT 3 antagonist (K i = 2.9 nM).Azasetron hydrochloride 준비 용품 및 원자재
원자재
준비 용품
Azasetron hydrochloride 공급 업체
글로벌( 176)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
Azasetron hydrochloride 관련 검색:
티오판산-메틸 테트라메틸피라진 쿠레톡심메틸 2,3,5-트리메틸피라진 살리실산 메틸 아세트산 메틸 클로로디플루오르메탄 브롬화 메틸
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