Dolutegravir Impurity 8

Dolutegravir Impurity 8 구조식 이미지
카스 번호:
2244161-72-4
상품명:
Dolutegravir Impurity 8
동의어(영문):
Durutevir impurity 12;Dolutegravir Impurity 59;2,6-Di fluoro Dolutegravir;Dolutegravir 2,6-difluoro Impurity;2,6 Difluoro dolutegravir sodium salt;1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-;Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity);4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir;(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB88117623
분자식:
C20H19F2N3O5
포뮬러 무게:
419.38
MOL 파일:
2244161-72-4.mol

Dolutegravir Impurity 8 속성

끓는 점
664.9±55.0 °C(Predicted)
밀도
1.53±0.1 g/cm3(Predicted)
산도 계수 (pKa)
4.50±1.00(Predicted)

안전

Dolutegravir Impurity 8 C화학적 특성, 용도, 생산

용도

4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity 8 준비 용품 및 원자재

원자재

준비 용품


Dolutegravir Impurity 8 공급 업체

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