1-Deoxynojirimycin
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1-Deoxynojirimycin 속성
- 녹는점
- 195-196°C
- 끓는 점
- 361.1±42.0 °C(Predicted)
- 밀도
- 1.456±0.06 g/cm3(Predicted)
- 증기압
- 0Pa at 25℃
- RTECS 번호
- TN4350300
- 저장 조건
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 최대 25 mg/ml의 물에 용해됩니다.
- 산도 계수 (pKa)
- 13.77±0.70(Predicted)
- 물리적 상태
- 가루
- 색상
- 하얀색
- 수용성
- 물, 디메틸설폭사이드 및 메탄올에 용해됩니다.
- BRN
- 3588039
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. 증류수 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.
- LogP
- -1.8
- CAS 데이터베이스
- 19130-96-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
안전지침서 | 24/25 | ||
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WGK 독일 | 1 | ||
HS 번호 | 29329990 |
1-Deoxynojirimycin C화학적 특성, 용도, 생산
화학적 성질
White Crystalline Solid출처
1-Deoxynojirimycin (DNJ), a product of fermentation, exists in mulberry leaves and Commelina communis (dayflower) as well as is isolated from several bacterial strains such as Bacillus and Streptomyces species. Mulberry, a common deciduous plant, belongs to the genus Morus (Moraceae family). Numerous researchers have reported the DJN contents in different parts and various varieties of mulberry. Various mulberry varieties contain DNJ contents ranging between 0.68 and 2.78 mg/gm, while this fraction varies between 1.57 and 3.48 mg/gm in different Chinese mulberry leaves. Moreover, mulberry shoots contain the highest contents of DNJ, followed by young mulberry leaves. Mature leaves of mulberry contain the least content of DNJ. All the mulberry leave groups showed a 1–2-fold increase in DNJ contents compared to unfermented mulberry leaf powder extract (UFMLE). Additionally, fermented mulberry leaf powder extract exhibited higher α-glucosidase activity than UFMLE. DNJ-rich food products can be prepared by fermenting mulberry leaves using the above-mentioned fermenting agents[6].용도
An alpha-glucosidase inhibitor. Interferes with normal processing of N-linked glycoproteins.(+)-1-Deoxynojirimycin acts as an inhibitor of alfa-glucosidase I and II and maltase-glucoamylase. It also inhibits mammalian glucosidase, intestinal and lysosmal, beta-glucosidase from sweet almonds, pancreatic alfa-amylase and amyloglucosidase. Further, it serves as a enzyme enhancer for the treatment of Fabry and Pompe disease.정의
ChEBI: An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration.생물학적 활성
Inhibitor of glucosidase I (K i = 2.1 mM) and II (K i = 7 mM).1-Deoxynojirimycin 준비 용품 및 원자재
원자재
준비 용품
1-Deoxynojirimycin 공급 업체
글로벌( 393)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3777 | 58 |
Hengshui Haoye Co.,Ltd. | +86-2102300 +86-18632882519 |
hy@haoyecom.cn | China | 365 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
1-Deoxynojirimycin 관련 검색:
트라이클로로에틸렌 클로르테트라사이클린 할로페리돌 드로페리돌, 펜타닐 염산미노사이클린 피페리딘
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