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프로판디올(S-1,2)

프로판디올(S-1,2) 구조식 이미지

카스 번호:: 4254-15-3

한글명:: 프로판디올(S-1,2)

동의어(한글):: (S)-(+)-프로필렌글리콜;프로판디올(S-1,2);(S)-(\+)-프로필렌 글리콜;(S)-(+)-1,2-프로판디올

상품명:: (S)-(+)-1,2-Propanediol

동의어(영문):: (S)-Propane-1,2-diol;(S)-1,2-PROPANEDIOL;(2S)-1,2-Propanediol;S-1,2-Propancdiol;L-1,2-Propanediol;(S)-(+)-PROPANEDIOL;(+)-1,2-Propanediol;(2S)-propane-1,2-diol;1,2-Propanediol, (S)-;PROPYELENE GLYCOL pure

CBNumber:: CB9145670

분자식:: C3H8O2

포뮬러 무게:: 76.09

MOL 파일:: 4254-15-3.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 357

프로판디올(S-1,2) 속성

녹는점: -59 °C

알파: 16 º (c=neat)

끓는 점: 186-188 °C765 mm Hg(lit.)

밀도: 1.036 g/mL at 20 °C(lit.)

굴절률: n20/D 1.432(lit.)

인화점: 225 °F

저장 조건: Keep in dark place,Sealed in dry,Room Temperature

용해도: Miscible with acetone, chloroform, ethanol (95%), glycerin, and water; soluble at 1 in 6 parts of ether; not miscible with light mineral oil or fixed oils, but will dissolve some essential oils.

산도 계수 (pKa): 14.49±0.20(Predicted)

물리적 상태: 액체

색상: 무색의

Specific Gravity: 1.04

optical activity: [α]20/D +16.5°, neat

폭발한계: 2.6-12.6%(V)

수용성: 녹는

감도: Hygroscopic

Merck: 14,7855

BRN: 1718871

안정성: 휘발성 물질

CAS 데이터베이스: 4254-15-3(CAS DataBase Reference)

NIST: (S)-(+)-1,2-Propanediol(4254-15-3)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xn
위험 카페고리 넘버	36/37/38-22
안전지침서	24/25-36/37/39-26
WGK 독일	1
HS 번호	29053200

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

NFPA 704

	1
0		1

프로판디올(S-1,2) C화학적 특성, 용도, 생산

화학적 성질

Colorless to light yellow liqui

용도

(S)-(+)-1,2-Propanediol acts as an organic solvent and diluent used in pharmaceutical preparations. It is also used as a chiral synthetic intermediate and substrate for enzyme studies.

생산 방법

Propylene is converted to chlorohydrin by chlorine water and hydrolyzed to 1,2-propylene oxide. With further hydrolysis, 1,2- propylene oxide is converted to propylene glycol.

Pharmaceutical Applications

Propylene glycol has become widely used as a solvent, extractant, and preservative in a variety of parenteral and nonparenteral pharmaceutical formulations. It is a better general solvent than glycerin and dissolves a wide variety of materials, such as corticosteroids, phenols, sulfa drugs, barbiturates, vitamins (A and D), most alkaloids, and many local anesthetics.
As an antiseptic it is similar to ethanol, and against molds it is similar to glycerin and only slightly less effective than ethanol. Propylene glycol is commonly used as a plasticizer in aqueous film-coating formulations.
Propylene glycol is also used in cosmetics and in the food industry as a carrier for emulsifiers and as a vehicle for flavors in preference to ethanol, since its lack of volatility provides a more uniform flavor.

저장

At cool temperatures, propylene glycol is stable in a well-closed container, but at high temperatures, in the open, it tends to oxidize, giving rise to products such as propionaldehyde, lactic acid, pyruvic acid, and acetic acid. Propylene glycol is chemically stable when mixed with ethanol (95%), glycerin, or water; aqueous solutions may be sterilized by autoclaving.
Propylene glycol is hygroscopic and should be stored in a wellclosed container, protected from light, in a cool, dry place.

비 호환성

Propylene glycol is incompatible with oxidizing reagents such as potassium permanganate.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (dental preparations; IM and IV injections; inhalations; ophthalmic, oral, otic, percutaneous, rectal, topical, and vaginal preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

프로판디올(S-1,2) 준비 용품 및 원자재

원자재

(S)-(-)-Propylene oxide R-(-)-프로필렌 글라이콜 프로필렌 염소(기체)

준비 용품

(S)-1,2-프로판디올카보네이트

프로판디올(S-1,2) 공급 업체

글로벌( 357)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5892	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20287	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18775	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58

프로판디올(S-1,2) 관련 검색:

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