H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE

H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE 구조식 이미지
카스 번호:
960129-66-2
상품명:
H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE
동의어(영문):
EDF;BCDFII;IL-5 from mouse;H-Asn-Asn-Trp-Asn-Asn-OH;EXTRACELLULAR DEATH FACTOR;Extracellular Death Factor, EDF;H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE;Extracellular Death Factor trifluoroacetate salt;Extracellular death factor (synthetic Escherichia coli);L-Asparaginyl-L-asparaginyl-L-tryptophyl-L-asparaginyl-L-asparagine
CBNumber:
CB92468432
분자식:
C27H36N10O10
포뮬러 무게:
660.64
MOL 파일:
960129-66-2.mol

H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE 속성

끓는 점
1452.5±65.0 °C(Predicted)
밀도
1.493±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble; Water: Soluble
산도 계수 (pKa)
3.13±0.10(Predicted)
물리적 상태
동결건조된
색상
무색의
시퀀스
H-Asn-Asn-Trp-Asn-Asn-OH

안전

WGK 독일 3

H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE C화학적 특성, 용도, 생산

용도

Extracellular Death Factor (ECF) is the dramatic name given to an interesting linear pentapeptide produced by E. coli, first identified by Engelberg-Kulka and colleagues in 2007 and published in Science. ECF acts as a quorum sensing agent, regulating bacterial cell density by balancing the levels of toxin and antitoxin via mazEF-mediated cell death genes.

일반 설명

IL-5 (interleukin 5) is a Th2 (T helper 2) cytokine that is predominantly produced by T lymphocytes, and to a lower extent by mast cells, type 2 innate lymphoid (ILC2) cells, and eosinophils.
Recombinant murine IL-5 is a 26.2kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Biochem/physiol Actions

IL-5 (interleukin 5) was initially identified as a stimulant of antibody production by activated B cells. It has recently been shown to be a key factor in eosinophil differentiation and proliferation. It is also implicated in the pathogenesis of asthma, atopy, hypereosinophilic syndromes, and parasitic infections. In distal lung, IL-5 recruits eosinophils and modulates inflammatory or immune cells in the microenvironment, thus, promoting lung metastasis in cancer.

H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE 준비 용품 및 원자재

원자재

준비 용품


H-ASN-ASN-TRP-ASN-ASN-OH TRIFLUOROACETATE 공급 업체

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