ABP688

ABP688 구조식 이미지
카스 번호:
924298-51-1
상품명:
ABP688
동의어(영문):
ABP688;ABP 924298-51-1;3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime;3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime;2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
CBNumber:
CB92669578
분자식:
C15H16N2O
포뮬러 무게:
240.3
MOL 파일:
924298-51-1.mol

ABP688 속성

끓는 점
361.4±52.0 °C(Predicted)
밀도
1.03±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO: 100 mM
물리적 상태
고체
산도 계수 (pKa)
2.78±0.19(Predicted)
색상
Light brown to brown

안전

ABP688 C화학적 특성, 용도, 생산

효소 저해제

This high-affinity mGluR antagonist (FW = 240.31 g/mol; CAS 924298- 51-1; Soluble to 100 mM in DMSO; 50 mM in 1 eq. HCl), also named 3- [2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime, targets the human metabolotrophic glutamate receptor-5 (mGluR5) (Ki = 1.7 nM) and inhibits glutamate-induced calcium release from Ltk-cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Indeed, [11C]- ABP688 is a useful PET tracer for in vivo imaging of the mGluR5 in rodents.

ABP688 준비 용품 및 원자재

원자재

준비 용품


ABP688 공급 업체

글로벌( 16)공급 업체
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Aladdin Scientific
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Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
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Shanghai Hongye Biotechnology Co. Ltd 400-9205774
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
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Bide Pharmatech Ltd. 400-1647117 15221909166
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TargetMol Chemicals Inc. 4008200310
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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8739 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826
market@aladdin-e.com China 48467 58
United States Biological --
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