Aprepitant Impurity 6

Aprepitant Impurity 6 구조식 이미지
카스 번호:
170902-81-5
상품명:
Aprepitant Impurity 6
동의어(영문):
1S, 2R, 3S-Aripitan;Aprepitant Impurity 5(S,R,S-Isomer);Fosaprepitant Dimeglumine Impurity A;Arepitam impurity isomers (1S, 2R, 3S);Fosaprepitant Dimeglumine EP Impurity A;Aprepitant impurity 9/(1S,2R,3S)-Aprepitant;[1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer;5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber:
CB93146511
분자식:
C23H21F7N4O3
포뮬러 무게:
534.43
MOL 파일:
170902-81-5.mol

Aprepitant Impurity 6 속성

밀도
1.51±0.1 g/cm3(Predicted)
산도 계수 (pKa)
8.06±0.20(Predicted)

안전

Aprepitant Impurity 6 C화학적 특성, 용도, 생산

용도

[1(S)-Phenylethoxy]-Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 6 준비 용품 및 원자재

원자재

준비 용품


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