GSK106 (hydrochloride)
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GSK106 (hydrochloride) 속성
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- 물리적 상태
- 결정성 고체
- 색상
- Off-white to light yellow
안전
GSK106 (hydrochloride) C화학적 특성, 용도, 생산
개요
Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199 . It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC50s > 100 μM). See the Structural Genomics Consortium (SGC) website for more information on both GSK484 and GSK106.용도
(3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride is structurally similar to (3-Amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone TFA Salt (G797395) and is suitable to use as a control to identify inhibitors for protein arginine deiminase 4 (PAD4).GSK106 (hydrochloride) 준비 용품 및 원자재
원자재
준비 용품
GSK106 (hydrochloride) 공급 업체
글로벌( 29)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32063 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30241 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8467 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 |
757984502@qq.com | China | 892 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 |
orders@jknbiochem.com | China | 5221 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 |
China | 4456 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 |
2853530910@QQ.com | China | 8014 | 62 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6777 | 58 |
| DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9410 | 58 |