마트리신

마트리신 C화학적 특성, 용도, 생산

용도

Matrix metalloproteinase-7 (MMP7) human has been used in in silico analysis of MMP-7 proteolysis of perlecan.

일반 설명

Matrix metalloproteinase-7 (MMP7) also referred to as matrilysin is encoded by the gene mapped to human chromosome 11q21-q22. MMP7 is a smallest member of MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells.

Biochem/physiol Actions

Matrix metalloproteinase-7 (MMP-7) catalyzes the cleavage of extracellular matrix (ECM) proteins such as proteoglycans, fibronectin, entactin, laminin, collagen III/ IV/ V/ IX/ X/ XI, type I/ II/ IV/ V gelatins, and elastin. Matrix metalloproteinase-7 facilitates initial stages of tumor progression. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. Overexpression of MMP7 is observed in various human cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Increased expression of MMP7 is also associated with pathogenesis of demyelinating multiple sclerosis (MS) lesions. Both in silico and in vitro studies show that MMP7 degrades glycosylated and basement membrane bound perlecan and plays a vital role in prostate cancer cell invasion.

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원자재

준비 용품

마트리신 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Wuhan Chemstan Biotechnology Co., Ltd.	027-65317797 15926423062	422450190@qq.com	China	10022	58
Shanghai Yaji Biological Technology Co., Ltd.	021-34661275 15301693058	yajikit@163.com	China	8638	58
Shanghai Huzhen Industrial Co., LTD	021-60345367 13916550749	sales@shzbio.com	China	9965	58
AntibodySystem	17762345272 18162686757	biolab-reagents@atagenix.com	China	9817	58
ACROBiosystems	18514007688	jiaxin.zhao@acrobiosystems.com	China	983	58
United States Biological	--	sales@advtechind.com	United States	6106	58