Anti-Histone Deacetylase 2 (HDAC2) antibody, Mouse monoclonal has been used in:
co-immunoprecipitation
chromatin immunoprecipitation (ChIP)
western blot
immunohistochemistry
enzyme linked immunosorbent assays (ELISA)
일반 설명
Anti-Histone Deacetylase 2 (HDAC2) antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the HDAC2-62 hybridoma produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to the C-terminal region of human histone deacetylase 2 (amino acid residues with N-terminal added cysteine) conjugated to maleimide-activated KLH. Histone deacetylase 2 (HDAC2) is the catalytic subunits of different multiprotein regulatory complexes.
Biochem/physiol Actions
Histone Deacetylases including HDAC′s 1-10 facilitate transcriptional repression and nucleosome condensation. Abnormal recruitment of HDACs by various oncoproteins may occur in certain neoplastic diseases. Inhibition of HDAC2 activity by valproic acid induces proteasomal degradation of HDAC2.
Anti-Histone Deacetylase 2 (HDAC2) antibody, Mouse monoclonal 준비 용품 및 원자재
원자재
준비 용품
Anti-Histone Deacetylase 2 (HDAC2) antibody, Mouse monoclonal 공급 업체
