LD50 in male and female rats, male and female mice (mg/kg): >10,000, >10,000 orally; in male and female rats (mg/kg): >5000 dermally (Araki)
기존화학 물질
KE-34243
그림문자(GHS):
신호 어:
Warning
유해·위험 문구:
암호
유해·위험 문구
위험 등급
범주
신호 어
그림 문자
P- 코드
H410
장기적 영향에 의해 수생생물에 매우 유독함
수생 환경유해성 물질 - 만성
구분 1
경고
P273, P391, P501
예방조치문구:
P273
환경으로 배출하지 마시오.
P391
누출물을 모으시오.
P501
...에 내용물 / 용기를 폐기 하시오.
플루토라닐 C화학적 특성, 용도, 생산
용도
Flutolanil is used to control Basidiomycetes diseases in rice,
cereals, sugar beet and other crops.
상품명
MONCUT
Safety Profile
Low toxicity by ingestion, skincontact, intraperitoneal, and subcutaneous routes. Whenheated to decomposition it emits toxic vapors of NOx andF??.
신진 대사 경로
Flutolanil is an analogue of mepronil in which the methyl group
is replaced by trifluoromethyl. Both compounds have systemic activity.
This change in structure should render flutolanil more biostable by
hindering hydrolysis and removing the option of methyl hydroxylation
and further oxidation. This seems to be borne out in practice in that
most of the metabolism of flutolanil occurs via O-dealkylation and aryl
hydroxylation. Hydrolysis has not been detected.
Mode of action
Flutolanil is a SDHI (Succinate-dehydrogenase inhibitor) with narrow spectrum. Flutolanil has inhibitory effect against development of each step of the infection cycle. Inhibition of invasion from sclerotium and mycelial growth result in preventive and curative effect in infection, respectively。