SPARSOMYCIN
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SPARSOMYCIN 속성
- 녹는점
- 208-209° (dec)
- 알파
- D25 +69° (c = 0.5 in water)
- 밀도
- 1.3893 (rough estimate)
- 굴절률
- 1.6390 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 8.67 in water, 9.05 in 40% ethanol
- 색상
- White to off-white
안전
| 위험품 표기 | T+ | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 28 | ||
| 안전지침서 | 28-36/37-45 | ||
| 유엔번호(UN No.) | UN 2811 6.1/PG 2 | ||
| RTECS 번호 | WG5850000 | ||
| 독성 | LD50 in dogs, rats, mice (mg/kg): 0.5-1.0, 2.25, 4.32 i.v. (Ottenheijm, 1986); LD50 i.p. in mice: 2.4 mg/kg (Owen) |
SPARSOMYCIN C화학적 특성, 용도, 생산
개요
Sparsomycin is a bacterial metabolite and a nucleoside analog of uracil that has been found in S. sparsogenes and has diverse biological activities. It is active against KB carcinoma cells, Gram-positive and Gram-negative bacteria, and fungi. Sparsomycin is an inhibitor of peptidyl transferase that interferes with tRNA binding to the A-site of the peptidyl transfer center and increases the binding of peptidyl-tRNA to the P-site. It inhibits protein synthesis in bacteria, archaea, and eukaryotes. Sparsomycin reduces tumor growth in a P388 mouse leukemia model and in a Walker 256 carcinosarcoma rat model.용도
Sparsomycin is an antibiotic that binds to active site and exit tunnel hydrophobic crevices of peptidyltransferase center of Haloarcula marismortui large ribosomal subunit.SPARSOMYCIN 준비 용품 및 원자재
원자재
준비 용품
SPARSOMYCIN 공급 업체
글로벌( 19)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49999 | 58 |
| BOC Sciences | 16314854226 |
info@bocsci.com | United States | 9926 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 |
sales@mitachieve.com | China | 8864 | 58 |
| Hubei Enxing Biotechnology Co., Ltd | 16621771607 |
exbio_tech@163.com | China | 8261 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8739 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 |
cb5@aikonchem.com | China | 10529 | 58 |