니코틴산단핵산염

니코틴산단핵산염
니코틴산단핵산염 구조식 이미지
카스 번호:
321-02-8
한글명:
니코틴산단핵산염
동의어(한글):
니코틴산단핵산염
상품명:
NICOTINIC ACID MONONUCLEOTIDE
동의어(영문):
β-NaMN;β-Nicotinic Acid Mon;Nicotinic Acid Ribotide;Nicotinic Mononucleotide;nicotinatemononucleotide;Nicotinate Ribonucleotide;Nicotinic Acid Ribonucleotide;NICOTINIC ACID MONONUCLEOTIDE;β-NicotinicAcidMononucleotide;3-Carboxy-1-methylpyridiniumiodid
CBNumber:
CB9670381
분자식:
C11H14NO9P
포뮬러 무게:
335.2
MOL 파일:
321-02-8.mol
MSDS 파일:
SDS

니코틴산단핵산염 속성

녹는점
>115°C (dec.)
저장 조건
−20°C
용해도
메탄올(약간 용해됨, 가열), 물(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
안정성
흡습성
InChI
InChI=1/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/s3
InChIKey
JOUIQRNQJGXQDC-NLNRFTKUNA-N
SMILES
[C@@H]1([C@H](O)[C@H](O)[C@@H](COP([O-])(=O)O)O1)[N+]1C=CC=C(C(=O)O)C=1 |&1:0,1,3,5,r|

안전

WGK 독일 3

니코틴산단핵산염 C화학적 특성, 용도, 생산

용도

A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.

Synthesis

Nicotinic acid mononucleotide is prepared by the reaction of 2,3-dicarboxypyridine and 5-phosphoribosyl-1-pyrophosphate. The steps are as follows:
With phosphoribosyl pyrophosphate-quinolinate phosphoribosyltransferase; magnesium chloride In aq. phosphate buffer at 37℃; for 6h; pH=7.0; Enzymatic reaction.
Nicotinic acid mononucleotide synthesis

니코틴산단핵산염 준비 용품 및 원자재

원자재

준비 용품


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