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Avermectin A1a, 5-O-demethyl-22,23-dihydro-

Avermectin A1a, 5-O-demethyl-22,23-dihydro- 구조식 이미지

카스 번호:: 71827-03-7

상품명:: Avermectin A1a, 5-O-demethyl-22,23-dihydro-

동의어(영문):: Ivermectin B1a;IvermectinH2B1a;Ivermectin B1a (>85%);Ivermectin Impurity 3;Dihydroavermectin B1a;22,23-dihydroavermectin B1a in Methanol;5-O-Demethyl-22,23-dihydroavermectin A1a;22,23-Dihydro-5-O-demethylavermectin A1a;Avermectin A1a, 5-O-demethyl-22,23-dihydro-;Ivermectin 2-epimer (Dihydro Avermectin B1a)

CBNumber:: CB9928288

분자식:: C48H74O14

포뮬러 무게:: 875.09

MOL 파일:: 71827-03-7.mol

속성

안전

용도

공급 업체 58

Avermectin A1a, 5-O-demethyl-22,23-dihydro- 속성

녹는점: 155-157°

끓는 점: 717.97°C (rough estimate)

밀도: 1.0683 (rough estimate)

굴절률: 1.6130 (estimate)

저장 조건: Store at -20°C

용해도: DMSO에 용해됨

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 12.42±0.70(Predicted)

색상: 하얀색

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H301	삼키면 유독함	급성 독성 물질 - 경구	구분 3	위험		P264, P270, P301+P310, P321, P330,P405, P501

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P310	삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P321	(…) 처치를 하시오.
P330	입을 씻어내시오.
P405	밀봉하여 저장하시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	0
3		0

Avermectin A1a, 5-O-demethyl-22,23-dihydro- C화학적 특성, 용도, 생산

개요

Ivermectin B_1a is the main component (>80%) of the anthelmintic ivermectin, which also contains ivermectin B_1b (<20%; ). It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function (EC₅₀ = 104 nM). Formulations containing ivermectin inhibit replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero/hSLAM cells.

정의

ChEBI: A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin.

Avermectin A1a, 5-O-demethyl-22,23-dihydro- 준비 용품 및 원자재

원자재

준비 용품

4a-Hydroxy Ivermectin

Avermectin A1a, 5-O-demethyl-22,23-dihydro- 공급 업체

글로벌( 58)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32072	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52925	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323658 +86-18168183658	sales1@artkmedchem.com	China	39004	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
QUALITY CONTROL SOLUTIONS LTD.	0755-66853366; 13670046396	ORDERS@QCSRM.COM	China	24326	58
Guangzhou PI PI Biotech Inc	020-81716320 +86-13602409664	Sales@pipitech.com	China	3633	55
BioBioPha Co., Ltd.	0871-65217109 13211707573;	y.liu@mail.biobiopha.com	China	5653	65
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18043	56
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65

Avermectin A1a, 5-O-demethyl-22,23-dihydro- 관련 검색:

3,4-Dihydro IverMectin :Ivermectin B1a monosaccharide Avermectin B1a Ivermectin Ivermectin aglycone Avermectin B1b 28-Oxo IverMectin B1a (IMpurity) 2-Methyltetrahydropyran Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- rac-2,3-Dehydro-3,4-dihydro IverMectin IverMectin B1 Aglycon Ivermectin