dehydroemetine
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dehydroemetine 속성
- 녹는점
- 94-96°
- 알파
- D -183°
- 끓는 점
- 604.7±55.0 °C(Predicted)
- 밀도
- 1.19±0.1 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 산도 계수 (pKa)
- 8.86±0.40(Predicted)
- 물리적 상태
- Solid
- 색상
- Off-white to light yellow
안전
dehydroemetine C화학적 특성, 용도, 생산
Pharmaceutical Applications
The synthetic racemic derivative of the plant alkaloid emetine. Formulated as the hydrochloride for intramuscular administration. Like the parent compound, emetine, it inhibits E. histolytica at concentrations of 1–10 mg/L in vitro, but it is more active than the parent in animal models. Drugresistance in E. histolytica is rare.No human pharmacokinetic data are available. A halflife of 2 days, compared with 5 days for emetine, has been reported. There is selective tissue binding and accumulation in the liver, lung, spleen and kidney.
It is considerably less toxic than emetine, possibly because it is more rapidly eliminated. Nevertheless, nausea, vomiting, diarrhea and abdominal cramps frequently occur. Neuromuscular effects have also been reported. More serious cardiotoxic effects can lead to electrocardiogram (EGG) changes, tachycardia and a drop in blood pressure.
It was formerly used as a second-line treatment in severe intestinal or hepatic amebiasis, but is no longer recommended for use.
dehydroemetine 준비 용품 및 원자재
원자재
준비 용품
dehydroemetine 공급 업체
글로벌( 11)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21676 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 26267 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 |
psaitong@jm-bio.com | China | 12308 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 |
psaitong@jm-bio.com | China | 29778 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 |
1046@dideu.com | China | 10011 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24017 | 58 |