2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide suppliers
2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
- CAS:
- 108605-62-5
- MF:
- C12H9F3N2O2
- MW:
- 270.21
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Properties
- Melting point:
- 229-232°C
- Boiling point:
- 410.8±45.0 °C(Predicted)
- Density
- 1.424±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
- form
- Solid
- pka
- 5.20±0.50(Predicted)
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P405-P501
- Hazard Codes
- Xn
- Risk Statements
- 22
- HS Code
- 2926900005
- Toxicity
- mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),United States Patent Document. Vol. #5494911,
Use
The active metabolite of Leflunomide, 2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide can be used as a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis.
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