Azasetron hydrochloride suppliers
Azasetron hydrochloride
- CAS:
- 123040-16-4
- MF:
- C17H21Cl2N3O3
- MW:
- 386.27
Suppliers by country/region
Company Type
Properties
- Melting point:
- 281° (dec); mp 305° (dec) (Kawakita)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- White solid.
- color
- White
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H361
- Precautionary statements
- P201-P202-P281-P308+P313-P405-P501
- Toxicity
- LD50 in male, female rats (mg/kg): 135, 132 i.v. (Takagi)
Use
Nazasetron (azasetron) hydrochloride is the fourth in the class of highly potent 5- HT3 receptor antagonists to reach the market for prophylaxis of severe nausea and vomiting induced by cytotoxic chemotherapy and by total body X-radiation. In a study with 146 cancer patients suffering from emesis induced by cisplatin, nazasetron was reported to be markedly effective in 72% of subjects. Nazasetron is devoid of dopamine D2 receptor blocking activity and therefore is free of the extrapyrimidal side effects associated with other commonly used antiemetics such as metoclopramide and domperidone. Nazasetron has been reported to be potentially useful for the treatment of gastrointestinal motility dysfunction, such as gastric stasis, vomiting and irritable bowel syndrome.
151 supplier list of "Azasetron hydrochloride"
$7.00/ 1kg
- Product Name:Azasetron hydrochloride
- Products Intro:Purity: 99% | Package: 1kg;7USD
- Company Type: Reagent
- Country/Region: CHINA
$1.10/ 1g
- Product Name:Azasetron hydrochloride
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA