Azithromycin manufacturers and suppliers

Azithromycin suppliers

Properties

Melting point:: 113-115°C

alpha: D20 -37° (c = 1 in CHCl3)

Boiling point:: 822.1±65.0 °C(Predicted)

Density: 1.18±0.1 g/cm3(Predicted)

storage temp.: Sealed in dry,2-8°C

solubility: Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride.

form: Solid

pka: pKa 8.74 (H2O t=25 I=0.167) (Uncertain);9.45(H2O t=25 I=0.167) (Uncertain)

color: White to Off-White

optical activity: [α]/D 45±2°, c = 1% in ethanol

BCS Class: 4

Stability:: Stable. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H317-H334

Precautionary statements: P261-P280-P342+P311

Hazard Codes: Xi,Xn

Risk Statements: 42/43

Safety Statements: 22-36/37-45

WGK Germany: 2

RTECS: RN6960000

HS Code: 29419090

Toxicity: LD50 oral in rat: > 2gm/kg

Use

Azithromycin is a semi-synthetic, ring-expanded erythromycin produced by a Beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive methylation. Azithromycin was the first of the azalides and was designed to improve the stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria. Since its discovery in 1980 by Djokic and co-workers, azithromycin has enjoyed considerable therapeutic success.

You can find Azithromycin suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.