TMC-207 suppliers
TMC-207
- CAS:
- 843663-66-1
- MF:
- C32H31BrN2O2
- MW:
- 555.5
Suppliers by country/region
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Properties
- Melting point:
- 104 °C
- Boiling point:
- 702.7±60.0 °C(Predicted)
- Density
- 1.322±0.06 g/cm3(Predicted)
- storage temp.
- Room temperature
- solubility
- Soluble in DMSO (10 mg/ml)
- form
- solid
- pka
- 13.05±0.29(Predicted)
- color
- White
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS08,GHS09,GHS06
- Signal word
- Danger
- Hazard statements
- H400-H373-H301-H410
- Precautionary statements
- P273-P391-P501-P264-P270-P301+P310-P321-P330-P405-P501-P273-P391-P501-P260-P314-P501
- HS Code
- 2933499090
Use
Bedaquiline (also known as TMC207 and R207910) is a diarylquinoline that was discovered from a high-throughput, whole-cell screening strategy with Mycobacterium smegmatis used as a surrogate for M. tuberculosis. Bedaquiline is a single enantiomer of an initial screening hit. Bedaquiline has potent and selective activity against mycobacteria, and is active against both drug-sensitive and drug-resistant M. tuberculosis. The mechanism of action of bedaquiline is unique amongst anti-TB drugs and involves inhibition of mycobacterial ATP synthase; it is not active against human ATP synthase. Bedaquiline has in vivo activity in numerous preclinical models of TB infection, alone and in combination with other anti-TB agents, and has bactericidal activity in established TB infection models.
165 supplier list of "TMC-207"
$0.00/ 1g
- Product Name:Bedaquiline
- Products Intro:Purity: 98% HPLC | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$32.00-1.30 / 1KG
- Product Name:TMC-207
- Products Intro:Purity: 99% | Package: 1KG;32USD|1000KG;1.3USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
- Product Name:TMC-207
- Products Intro:Purity: 98% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA