ACTINONIN manufacturers and suppliers

ACTINONIN suppliers

Properties

Melting point:: 137-139°C

Density: 1.139±0.06 g/cm3(Predicted)

storage temp.: -20°C

solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).

pka: 9.19±0.20(Predicted)

form: White to off-white powder.

color: White

BRN: 1555250

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

CAS DataBase Reference: 13434-13-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338

Safety Statements: 22-24/25

WGK Germany: 3

RTECS: RG9900700

Use

(-)-Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of aminopeptidase M and leucine aminopeptidase. Actinonin has observed to be an inhibitor of peptide deformylase, meprin A, and thermolysin. Actinonin also inhibits tumor cell invasion and matrix degradation along with displayed antitumor activity in vitro and in vivo as well as acting as an apoptotic inducer.

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