AGI6780 suppliers
AGI6780
- CAS:
- 1432660-47-3
- MF:
- C21H18F3N3O3S2
- MW:
- 481.51
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Properties
- Density
- 1.52±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥22.25 mg/mL in DMSO; insoluble in H2O; ≥100.8 mg/mL in EtOH
- form
- solid
- pka
- 11.78±0.20(Predicted)
- color
- White to off-white
Safety Information
- HS Code
- 2935909099
Use
AGI-6780 potently reduce (R)-2-hydroxyglutarate (2HG) levels in cell lines ectopically overexpressing IDH2/R140Q with EC50 of 20 nM, with excellent selectivity against other dehydrogenases. AGI-6780 reverses the IDH2/R140Q-induced differentiation block in TF-1 cells, and induces blast differentiation in primary human IDH2/R140Q AML patient samples.
89 supplier list of "AGI6780"
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