Apatinib suppliers
Apatinib
- CAS:
- 811803-05-1
- MF:
- C24H23N5O
- MW:
- 397.47
Properties
- Boiling point:
- 578.2±50.0 °C(Predicted)
- Density
- 1.27
- storage temp.
- Store at -20°C
- solubility
- >49.4mg/ml in DMSO
- form
- Powder
- pka
- 11.93±0.70(Predicted)
Safety Information
Use
Apatinib mesylate, discovered by Advenchen Laboratories (United States of America, USA) and co-developed by Jiangsu Hengrui Medicine Co. Ltd (China), was approved by the Chinese Food and Drug Administration (CFDA) in October 2014 for the treatment of metastatic gastric carcinoma. Apatinib mesylate is an oral tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor 2 (VEGFR2), which prevents new blood vessel formation selectively in tumor tissue.
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